Electrochemical Sensor Based on Carboxymethyl Cellulose-Coated Copper Nanoparticle Composite for Detection of Norfloxacin in Milk
A highly sensitive electrochemical sensor for the detection of norfloxacin (NFX) was constructed using CMC@Cu/CB composites, which were prepared from carboxymethyl cellulose (CMC)-coated copper nanoparticles (Cu NPs) and carbon black (CB). The structure and morphology of CMC@Cu/CB were characterized...
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China Food Publishing Company
2025-01-01
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| Series: | Shipin Kexue |
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| Online Access: | https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-1-021.pdf |
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| author | LI Shengnan, HU Minkang, QIN Boyang, YANG Wen, FENG Jun, DU Haijun |
| author_facet | LI Shengnan, HU Minkang, QIN Boyang, YANG Wen, FENG Jun, DU Haijun |
| author_sort | LI Shengnan, HU Minkang, QIN Boyang, YANG Wen, FENG Jun, DU Haijun |
| collection | DOAJ |
| description | A highly sensitive electrochemical sensor for the detection of norfloxacin (NFX) was constructed using CMC@Cu/CB composites, which were prepared from carboxymethyl cellulose (CMC)-coated copper nanoparticles (Cu NPs) and carbon black (CB). The structure and morphology of CMC@Cu/CB were characterized by scanning electron microscope (SEM), X-ray photoelectron spectroscopy (SPS), and X-ray diffraction (XRD). The CMC@Cu/CB/GCE sensor was prepared by drop-casting the composite suspension on the glassy carbon electrode (GCE) surface. The results showed that the CMC@Cu/CB/GCE sensor, which was in the form of uniformly dispersed spheres, had a good current response to NFX, with a linear range of 0.4–100.0 μmol/L and a limit of detection (LOD) of 0.24 μmol/L (RSN = 3). In addition, the modified electrode had good sensitivity and stability for the detection of NFX in real samples, and the spiked recoveries of NFX in milk extracts ranged from 98.8%–112.5%. Furthermore, thanks to the low price of raw materials used in the experimental process and the preparation extremely of low cost of the sensor, it is promising for actual applications. |
| format | Article |
| id | doaj-art-aa4b41e9741545a99b572f03fa3570ea |
| institution | Kabale University |
| issn | 1002-6630 |
| language | English |
| publishDate | 2025-01-01 |
| publisher | China Food Publishing Company |
| record_format | Article |
| series | Shipin Kexue |
| spelling | doaj-art-aa4b41e9741545a99b572f03fa3570ea2025-02-05T09:08:12ZengChina Food Publishing CompanyShipin Kexue1002-66302025-01-0146118419110.7506/spkx1002-6630-20240314-103Electrochemical Sensor Based on Carboxymethyl Cellulose-Coated Copper Nanoparticle Composite for Detection of Norfloxacin in MilkLI Shengnan, HU Minkang, QIN Boyang, YANG Wen, FENG Jun, DU Haijun0(1. School of Chemical Engineering, Guizhou University for Nationalities, Guiyang 550025, China; 2. Institute of Tea Research, Guizhou Academy of Agricultural Sciences, Guiyang 550006, China; 3. College of Chemistry and Chemical Engineering, Yili Normal University, Yining 835000, China)A highly sensitive electrochemical sensor for the detection of norfloxacin (NFX) was constructed using CMC@Cu/CB composites, which were prepared from carboxymethyl cellulose (CMC)-coated copper nanoparticles (Cu NPs) and carbon black (CB). The structure and morphology of CMC@Cu/CB were characterized by scanning electron microscope (SEM), X-ray photoelectron spectroscopy (SPS), and X-ray diffraction (XRD). The CMC@Cu/CB/GCE sensor was prepared by drop-casting the composite suspension on the glassy carbon electrode (GCE) surface. The results showed that the CMC@Cu/CB/GCE sensor, which was in the form of uniformly dispersed spheres, had a good current response to NFX, with a linear range of 0.4–100.0 μmol/L and a limit of detection (LOD) of 0.24 μmol/L (RSN = 3). In addition, the modified electrode had good sensitivity and stability for the detection of NFX in real samples, and the spiked recoveries of NFX in milk extracts ranged from 98.8%–112.5%. Furthermore, thanks to the low price of raw materials used in the experimental process and the preparation extremely of low cost of the sensor, it is promising for actual applications.https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-1-021.pdfelectrochemical sensor; norfloxacin; copper nanoparticles; carboxymethyl cellulose |
| spellingShingle | LI Shengnan, HU Minkang, QIN Boyang, YANG Wen, FENG Jun, DU Haijun Electrochemical Sensor Based on Carboxymethyl Cellulose-Coated Copper Nanoparticle Composite for Detection of Norfloxacin in Milk Shipin Kexue electrochemical sensor; norfloxacin; copper nanoparticles; carboxymethyl cellulose |
| title | Electrochemical Sensor Based on Carboxymethyl Cellulose-Coated Copper Nanoparticle Composite for Detection of Norfloxacin in Milk |
| title_full | Electrochemical Sensor Based on Carboxymethyl Cellulose-Coated Copper Nanoparticle Composite for Detection of Norfloxacin in Milk |
| title_fullStr | Electrochemical Sensor Based on Carboxymethyl Cellulose-Coated Copper Nanoparticle Composite for Detection of Norfloxacin in Milk |
| title_full_unstemmed | Electrochemical Sensor Based on Carboxymethyl Cellulose-Coated Copper Nanoparticle Composite for Detection of Norfloxacin in Milk |
| title_short | Electrochemical Sensor Based on Carboxymethyl Cellulose-Coated Copper Nanoparticle Composite for Detection of Norfloxacin in Milk |
| title_sort | electrochemical sensor based on carboxymethyl cellulose coated copper nanoparticle composite for detection of norfloxacin in milk |
| topic | electrochemical sensor; norfloxacin; copper nanoparticles; carboxymethyl cellulose |
| url | https://www.spkx.net.cn/fileup/1002-6630/PDF/2025-46-1-021.pdf |
| work_keys_str_mv | AT lishengnanhuminkangqinboyangyangwenfengjunduhaijun electrochemicalsensorbasedoncarboxymethylcellulosecoatedcoppernanoparticlecompositefordetectionofnorfloxacininmilk |