A cross-tissue transcriptome-wide association study identifies new susceptibility genes for benign prostatic hyperplasia

A cross-tissue transcriptome-wide association study identifies new susceptibility genes for benign prostatic hyperplasia

Abstract Benign prostatic hyperplasia (BPH) is a prevalent urinary system disorder. Despite evidence of a significant genetic component from previous studies, the specific pathogenic genes and biological mechanisms are still largely unknown. The study utilized the FinnGen R10 dataset, encompassing 1...

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Bibliographic Details
Main Authors: Li Wang, Si-yu Chen, Jian-wei Yang, Kang-yu Wang, Kun-peng Li, Shun Wan, Xiao-ran Li, Li Yang
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Subjects:
BPH
TWAS
UTMOST
Gene
Mendelian randomization
Online Access:https://doi.org/10.1038/s41598-025-87651-y
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