Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung
We present two cases of relapsed adenocarcinoma of the lung: a 50-year-old male and a 67-year-old male. Both patients had previously been treated with platinum-containing systemic chemotherapy. In both cases, significant clinical efficacy was demonstrated with combination chemotherapy consisting of...
Saved in:
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2012-01-01
|
| Series: | Case Reports in Oncological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2012/821280 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1849395470709817344 |
|---|---|
| author | Sae Wada Nobukazu Fujimoto Kenichi Gemba Michiko Asano Yasuko Fuchimoto Katsuichiro Ono Shinji Ozaki Takumi Kishimoto |
| author_facet | Sae Wada Nobukazu Fujimoto Kenichi Gemba Michiko Asano Yasuko Fuchimoto Katsuichiro Ono Shinji Ozaki Takumi Kishimoto |
| author_sort | Sae Wada |
| collection | DOAJ |
| description | We present two cases of relapsed adenocarcinoma of the lung: a 50-year-old male and a 67-year-old male. Both patients had previously been treated with platinum-containing systemic chemotherapy. In both cases, significant clinical efficacy was demonstrated with combination chemotherapy consisting of pemetrexed, carboplatin, and bevacizumab as salvage treatment. Adverse events were mild. This regimen might be a viable therapeutic option even after heavy treatment such as platinum-containing chemotherapy, especially for patients with preserved organ function and good performance status. |
| format | Article |
| id | doaj-art-aa02fe7e8c2d4e48bb3ba29cc837d264 |
| institution | Kabale University |
| issn | 2090-6706 2090-6714 |
| language | English |
| publishDate | 2012-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Oncological Medicine |
| spelling | doaj-art-aa02fe7e8c2d4e48bb3ba29cc837d2642025-08-20T03:39:36ZengWileyCase Reports in Oncological Medicine2090-67062090-67142012-01-01201210.1155/2012/821280821280Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the LungSae Wada0Nobukazu Fujimoto1Kenichi Gemba2Michiko Asano3Yasuko Fuchimoto4Katsuichiro Ono5Shinji Ozaki6Takumi Kishimoto7Department of Respiratory Medicine, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Minamiku, Okayama 7028055, JapanDepartment of Respiratory Medicine, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Minamiku, Okayama 7028055, JapanDepartment of Respiratory Medicine, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Minamiku, Okayama 7028055, JapanDepartment of Respiratory Medicine, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Minamiku, Okayama 7028055, JapanDepartment of Respiratory Medicine, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Minamiku, Okayama 7028055, JapanDepartment of Respiratory Medicine, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Minamiku, Okayama 7028055, JapanDepartment of Respiratory Medicine, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Minamiku, Okayama 7028055, JapanDepartment of Respiratory Medicine, Okayama Rosai Hospital, 1-10-25 Chikkomidorimachi, Minamiku, Okayama 7028055, JapanWe present two cases of relapsed adenocarcinoma of the lung: a 50-year-old male and a 67-year-old male. Both patients had previously been treated with platinum-containing systemic chemotherapy. In both cases, significant clinical efficacy was demonstrated with combination chemotherapy consisting of pemetrexed, carboplatin, and bevacizumab as salvage treatment. Adverse events were mild. This regimen might be a viable therapeutic option even after heavy treatment such as platinum-containing chemotherapy, especially for patients with preserved organ function and good performance status.http://dx.doi.org/10.1155/2012/821280 |
| spellingShingle | Sae Wada Nobukazu Fujimoto Kenichi Gemba Michiko Asano Yasuko Fuchimoto Katsuichiro Ono Shinji Ozaki Takumi Kishimoto Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung Case Reports in Oncological Medicine |
| title | Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung |
| title_full | Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung |
| title_fullStr | Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung |
| title_full_unstemmed | Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung |
| title_short | Successful Treatment with Pemetrexed, Carboplatin, and Bevacizumab for Platinum-Resistant Adenocarcinoma of the Lung |
| title_sort | successful treatment with pemetrexed carboplatin and bevacizumab for platinum resistant adenocarcinoma of the lung |
| url | http://dx.doi.org/10.1155/2012/821280 |
| work_keys_str_mv | AT saewada successfultreatmentwithpemetrexedcarboplatinandbevacizumabforplatinumresistantadenocarcinomaofthelung AT nobukazufujimoto successfultreatmentwithpemetrexedcarboplatinandbevacizumabforplatinumresistantadenocarcinomaofthelung AT kenichigemba successfultreatmentwithpemetrexedcarboplatinandbevacizumabforplatinumresistantadenocarcinomaofthelung AT michikoasano successfultreatmentwithpemetrexedcarboplatinandbevacizumabforplatinumresistantadenocarcinomaofthelung AT yasukofuchimoto successfultreatmentwithpemetrexedcarboplatinandbevacizumabforplatinumresistantadenocarcinomaofthelung AT katsuichiroono successfultreatmentwithpemetrexedcarboplatinandbevacizumabforplatinumresistantadenocarcinomaofthelung AT shinjiozaki successfultreatmentwithpemetrexedcarboplatinandbevacizumabforplatinumresistantadenocarcinomaofthelung AT takumikishimoto successfultreatmentwithpemetrexedcarboplatinandbevacizumabforplatinumresistantadenocarcinomaofthelung |