Acid-responsive CST@NPs enhanced diabetic wound healing through rescuing mitochondrial dysfunction

Acid-responsive CST@NPs enhanced diabetic wound healing through rescuing mitochondrial dysfunction

Diabetic ulcers (DUs) are persistent and challenging complications of diabetes. The consequences of DUs include a decline in functional status, increased risk of infection, hospitalization, and even death. Our study revealed a significant decrease in the levels of cortistatin (CST) in the skin tissu...

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Main Authors: Xuelian Zhang, Hang Li, Yang Liu, Jie Yu, Pengfei Zhang, Peiling Yu, Yuhao Liu, Suyi Jia, Lijuan Ling, Peng Li, Lei Li, Yueyao Wang, Tengxiao Huang, Gaoxin Jin, Yunpeng Zhao, Guoli Ma, Qinghao Yuan, Lei Zhu, Zhiyue Zhang, Hao Li, Weiwei Li
Format: Article
Language:English
Published: KeAi Communications Co., Ltd. 2025-02-01
Series:Bioactive Materials
Subjects:
Diabetic wound healing, Cortistatin
Nanoparticle
Acid-responsive
Mitochondria
Apoptosis
Online Access:http://www.sciencedirect.com/science/article/pii/S2452199X24004481
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