Investigation of Clinical Characteristics and Etiological Factors in Children with Molar Incisor Hypomineralization

Aim. The purpose of the present study was to evaluate the clinical defects and etiological factors potentially involved in the onset of MIH in a pediatric sample. Methods. 120 children, selected from the university dental clinic, were included: 60 children (25 boys and 35 girls; average age: 9.8 ± 1...

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Main Authors: Maria Rita Giuca, Maria Cappè, Elisabetta Carli, Lisa Lardani, Marco Pasini
Format: Article
Language:English
Published: Wiley 2018-01-01
Series:International Journal of Dentistry
Online Access:http://dx.doi.org/10.1155/2018/7584736
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author Maria Rita Giuca
Maria Cappè
Elisabetta Carli
Lisa Lardani
Marco Pasini
author_facet Maria Rita Giuca
Maria Cappè
Elisabetta Carli
Lisa Lardani
Marco Pasini
author_sort Maria Rita Giuca
collection DOAJ
description Aim. The purpose of the present study was to evaluate the clinical defects and etiological factors potentially involved in the onset of MIH in a pediatric sample. Methods. 120 children, selected from the university dental clinic, were included: 60 children (25 boys and 35 girls; average age: 9.8 ± 1.8 years) with MIH formed the test group and 60 children (27 boys and 33 girls; average age: 10.1 ± 2 years) without MIH constituted the control group. Distribution and severity of MIH defects were evaluated, and a questionnaire was used to investigate the etiological variables; chi-square, univariate, and multivariate statistical tests were performed (significance level set at p<0.05). Results. A total of 186 molars and 98 incisors exhibited MIH defects: 55 molars and 75 incisors showed mild defects, 91 molars and 20 incisors had moderate lesions, and 40 molars and 3 incisors showed severe lesions. Univariate and multivariate statistical analysis showed a significant association (p<0.05) between MIH and ear, nose, and throat (ENT) disorders and the antibiotics used during pregnancy (0.019). Conclusions. Moderate defects were more frequent in the molars, while mild lesions were more frequent in the incisors. Antibiotics used during pregnancy and ENT may be directly involved in the etiology of MIH in children.
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spelling doaj-art-a9fbcb2647cc4b10835af6b760f6134e2025-02-03T07:26:08ZengWileyInternational Journal of Dentistry1687-87281687-87362018-01-01201810.1155/2018/75847367584736Investigation of Clinical Characteristics and Etiological Factors in Children with Molar Incisor HypomineralizationMaria Rita Giuca0Maria Cappè1Elisabetta Carli2Lisa Lardani3Marco Pasini4Department of Surgical, Medical, Molecular Pathology and Critical Area, Dental and Oral Surgery Clinic, Unit of Pediatric Dentistry, University of Pisa, Via Savi 10, 56126 Pisa, ItalyDepartment of Surgical, Medical, Molecular Pathology and Critical Area, Dental and Oral Surgery Clinic, Unit of Pediatric Dentistry, University of Pisa, Via Savi 10, 56126 Pisa, ItalyDepartment of Surgical, Medical, Molecular Pathology and Critical Area, Dental and Oral Surgery Clinic, Unit of Pediatric Dentistry, University of Pisa, Via Savi 10, 56126 Pisa, ItalyDepartment of Surgical, Medical, Molecular Pathology and Critical Area, Dental and Oral Surgery Clinic, Unit of Pediatric Dentistry, University of Pisa, Via Savi 10, 56126 Pisa, ItalyDepartment of Surgical, Medical, Molecular Pathology and Critical Area, Dental and Oral Surgery Clinic, Unit of Pediatric Dentistry, University of Pisa, Via Savi 10, 56126 Pisa, ItalyAim. The purpose of the present study was to evaluate the clinical defects and etiological factors potentially involved in the onset of MIH in a pediatric sample. Methods. 120 children, selected from the university dental clinic, were included: 60 children (25 boys and 35 girls; average age: 9.8 ± 1.8 years) with MIH formed the test group and 60 children (27 boys and 33 girls; average age: 10.1 ± 2 years) without MIH constituted the control group. Distribution and severity of MIH defects were evaluated, and a questionnaire was used to investigate the etiological variables; chi-square, univariate, and multivariate statistical tests were performed (significance level set at p<0.05). Results. A total of 186 molars and 98 incisors exhibited MIH defects: 55 molars and 75 incisors showed mild defects, 91 molars and 20 incisors had moderate lesions, and 40 molars and 3 incisors showed severe lesions. Univariate and multivariate statistical analysis showed a significant association (p<0.05) between MIH and ear, nose, and throat (ENT) disorders and the antibiotics used during pregnancy (0.019). Conclusions. Moderate defects were more frequent in the molars, while mild lesions were more frequent in the incisors. Antibiotics used during pregnancy and ENT may be directly involved in the etiology of MIH in children.http://dx.doi.org/10.1155/2018/7584736
spellingShingle Maria Rita Giuca
Maria Cappè
Elisabetta Carli
Lisa Lardani
Marco Pasini
Investigation of Clinical Characteristics and Etiological Factors in Children with Molar Incisor Hypomineralization
International Journal of Dentistry
title Investigation of Clinical Characteristics and Etiological Factors in Children with Molar Incisor Hypomineralization
title_full Investigation of Clinical Characteristics and Etiological Factors in Children with Molar Incisor Hypomineralization
title_fullStr Investigation of Clinical Characteristics and Etiological Factors in Children with Molar Incisor Hypomineralization
title_full_unstemmed Investigation of Clinical Characteristics and Etiological Factors in Children with Molar Incisor Hypomineralization
title_short Investigation of Clinical Characteristics and Etiological Factors in Children with Molar Incisor Hypomineralization
title_sort investigation of clinical characteristics and etiological factors in children with molar incisor hypomineralization
url http://dx.doi.org/10.1155/2018/7584736
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