Extensive Epidermal Skin Loss Secondary to HSV Type One: Neonatal Management Challenges
We describe a rare case of a preterm neonate presenting at birth with extensive epidermal skin loss of over 90% due to disseminated herpes simplex virus type one infection. Differential diagnosis included aplasia cutis and epidermolysis bullosa. Serum PCR and mouth swabs confirmed HSV type one, and...
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| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Wiley
2019-01-01
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| Series: | Case Reports in Pediatrics |
| Online Access: | http://dx.doi.org/10.1155/2019/2459219 |
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| _version_ | 1832546151926071296 |
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| author | Rebecca J Calthorpe Emma Spencer Jane C Ravenscroft Ting S Tang Anna E Martinez Anjum Deorukhkar |
| author_facet | Rebecca J Calthorpe Emma Spencer Jane C Ravenscroft Ting S Tang Anna E Martinez Anjum Deorukhkar |
| author_sort | Rebecca J Calthorpe |
| collection | DOAJ |
| description | We describe a rare case of a preterm neonate presenting at birth with extensive epidermal skin loss of over 90% due to disseminated herpes simplex virus type one infection. Differential diagnosis included aplasia cutis and epidermolysis bullosa. Serum PCR and mouth swabs confirmed HSV type one, and the patient required three weeks of treatment with intravenous aciclovir, followed by oral aciclovir. We describe the management challenges and give practical solutions applicable to the care of a neonate presenting with widespread skin loss due to any aetiology. |
| format | Article |
| id | doaj-art-a9ece88f68064038acb137952f6d682a |
| institution | Kabale University |
| issn | 2090-6803 2090-6811 |
| language | English |
| publishDate | 2019-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pediatrics |
| spelling | doaj-art-a9ece88f68064038acb137952f6d682a2025-02-03T07:23:50ZengWileyCase Reports in Pediatrics2090-68032090-68112019-01-01201910.1155/2019/24592192459219Extensive Epidermal Skin Loss Secondary to HSV Type One: Neonatal Management ChallengesRebecca J Calthorpe0Emma Spencer1Jane C Ravenscroft2Ting S Tang3Anna E Martinez4Anjum Deorukhkar5Department of Neonatology, Nottingham University Hospitals NHS Trust, Nottingham, UKDepartment of Neonatology, Nottingham University Hospitals NHS Trust, Nottingham, UKDepartment of Dermatology, Nottingham University Hospitals NHS Trust, Nottingham, UKDepartment of Dermatology, Nottingham University Hospitals NHS Trust, Nottingham, UKDepartment of Dermatology, Great Ormond Street Hospitals, London, UKDepartment of Neonatology, Nottingham University Hospitals NHS Trust, Nottingham, UKWe describe a rare case of a preterm neonate presenting at birth with extensive epidermal skin loss of over 90% due to disseminated herpes simplex virus type one infection. Differential diagnosis included aplasia cutis and epidermolysis bullosa. Serum PCR and mouth swabs confirmed HSV type one, and the patient required three weeks of treatment with intravenous aciclovir, followed by oral aciclovir. We describe the management challenges and give practical solutions applicable to the care of a neonate presenting with widespread skin loss due to any aetiology.http://dx.doi.org/10.1155/2019/2459219 |
| spellingShingle | Rebecca J Calthorpe Emma Spencer Jane C Ravenscroft Ting S Tang Anna E Martinez Anjum Deorukhkar Extensive Epidermal Skin Loss Secondary to HSV Type One: Neonatal Management Challenges Case Reports in Pediatrics |
| title | Extensive Epidermal Skin Loss Secondary to HSV Type One: Neonatal Management Challenges |
| title_full | Extensive Epidermal Skin Loss Secondary to HSV Type One: Neonatal Management Challenges |
| title_fullStr | Extensive Epidermal Skin Loss Secondary to HSV Type One: Neonatal Management Challenges |
| title_full_unstemmed | Extensive Epidermal Skin Loss Secondary to HSV Type One: Neonatal Management Challenges |
| title_short | Extensive Epidermal Skin Loss Secondary to HSV Type One: Neonatal Management Challenges |
| title_sort | extensive epidermal skin loss secondary to hsv type one neonatal management challenges |
| url | http://dx.doi.org/10.1155/2019/2459219 |
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