Effect of chemico-mechanical preparation on root canal microbiology in a resource-limited setting: A longitudinal study
Background: Chemico-mechanical preparation is a crucial step in endodontic treatment, but its effectiveness in resource-limited settings is understudied. Aim: This study investigated the impact of chemico-mechanical preparation on root canal microbiology and assessed antimicrobial sensitivity of iso...
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| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Wolters Kluwer Medknow Publications
2025-04-01
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| Series: | SRM Journal of Research in Dental Sciences |
| Subjects: | |
| Online Access: | https://journals.lww.com/10.4103/srmjrds.srmjrds_98_24 |
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| Summary: | Background:
Chemico-mechanical preparation is a crucial step in endodontic treatment, but its effectiveness in resource-limited settings is understudied.
Aim:
This study investigated the impact of chemico-mechanical preparation on root canal microbiology and assessed antimicrobial sensitivity of isolated microorganisms.
Materials and Methods:
This longitudinal study involved 40 patients undergoing root canal therapy. Microbial samples were collected during chemico-mechanical preparation and analyzed using microscopy, culture, and sensitivity tests.
Results:
The microbial load varied significantly at different treatment stages, while the types of organisms were not significantly different. The isolates showed resistance to co-trimoxazole and ampicillin, and sensitivity to gentamicin and nitrofurantoin.
Conclusions:
Chemico-mechanical preparation effectively reduces microbial load and diversity in root canals, even in resource-limited settings. The study highlights the potential benefit of using nitrofurantoin, tetracycline, and gentamicin as intracanal medications. Findings underscore the importance of chemico-mechanical preparation in endodontic treatment, suggesting a revisit of the antiseptics used as routine intracanal medications. |
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| ISSN: | 2772-5243 2772-5251 |