Navigating the Collective: Nanoparticle-Assisted Identification of Leader Cancer Cells During Migration

Navigating the Collective: Nanoparticle-Assisted Identification of Leader Cancer Cells During Migration

Cancer-related deaths primarily occur due to metastasis, a process involving the migration and invasion of cancer cells. In most solid tumors, metastasis occurs through collective cell migration (CCM), guided by “cellular leaders”. These leader cells generate forces through actomyosin-mediated protr...

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Bibliographic Details
Main Authors: Anastasia Alexandrova, Elizaveta Kontareva, Margarita Pustovalova, Sergey Leonov, Yulia Merkher
Format: Article
Language:English
Published: MDPI AG 2025-01-01
Series:Life
Subjects:
metastasis
cytoskeletal mechanisms
metastatic potential
endocytosis
nanoparticle encapsulation
actin filaments
Online Access:https://www.mdpi.com/2075-1729/15/1/127
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