The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet

<b>Aim:</b> The purpose of the present study was to examine the effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet.<p> <b>Materials and Methods:</b> In this research, 24 male healthy Wistar Albino rats were divided into three equal grou...

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Main Authors: Deniz Uluışık, Ercan Keskin
Format: Article
Language:English
Published: Selcuk University Press
Series:Eurasian Journal of Veterinary Sciences
Subjects:
Online Access:http://eurasianjvetsci.org/pdf.php3?id=1109
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author Deniz Uluışık
Ercan Keskin
author_facet Deniz Uluışık
Ercan Keskin
author_sort Deniz Uluışık
collection DOAJ
description <b>Aim:</b> The purpose of the present study was to examine the effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet.<p> <b>Materials and Methods:</b> In this research, 24 male healthy Wistar Albino rats were divided into three equal groups as control (K), cholesterol (C) and ginseng + cholesterol (GC). During the 40 days experiment, the K group received a standard rat diet, whereas the C and GC groups were fed the same standard diet containing 5% cholesterol and 5% cholesterol +1 g/kg ginseng root powder, respectively. Anticoagulant blood samples were taken from all animals at the end of the study. In these blood samples, red and white blood cells, hemoglobin, hematocrit, granulocytes, lymphocytes, monocytes, mean red cell volume , mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration were measured with hemacell counter.<p> <b>Results:</b> Hemoglobin and hematocrit levels of C group significantly decreased compared to K group (P<0.05), while the same parameters of GC group were found to be statically higher than C group levels (P<0.05). In respect of the other parameters, there was no important changes depend on ginseng or/and cholesterol treatments.<p> <b>Conclusion:</b> It is stated that ginseng may improve the negative effect of hypercholesterolemia on hematologic parameters.
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institution Kabale University
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series Eurasian Journal of Veterinary Sciences
spelling doaj-art-a9bbea781e6d4d55acfce3ff2b36473b2025-02-03T11:25:40ZengSelcuk University PressEurasian Journal of Veterinary Sciences1309-69582146-195332148511109The effect of ginseng on some hematological parameters in rats fed cholesterol-rich dietDeniz UluışıkErcan Keskin<b>Aim:</b> The purpose of the present study was to examine the effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet.<p> <b>Materials and Methods:</b> In this research, 24 male healthy Wistar Albino rats were divided into three equal groups as control (K), cholesterol (C) and ginseng + cholesterol (GC). During the 40 days experiment, the K group received a standard rat diet, whereas the C and GC groups were fed the same standard diet containing 5% cholesterol and 5% cholesterol +1 g/kg ginseng root powder, respectively. Anticoagulant blood samples were taken from all animals at the end of the study. In these blood samples, red and white blood cells, hemoglobin, hematocrit, granulocytes, lymphocytes, monocytes, mean red cell volume , mean corpuscular hemoglobin and mean corpuscular hemoglobin concentration were measured with hemacell counter.<p> <b>Results:</b> Hemoglobin and hematocrit levels of C group significantly decreased compared to K group (P<0.05), while the same parameters of GC group were found to be statically higher than C group levels (P<0.05). In respect of the other parameters, there was no important changes depend on ginseng or/and cholesterol treatments.<p> <b>Conclusion:</b> It is stated that ginseng may improve the negative effect of hypercholesterolemia on hematologic parameters.http://eurasianjvetsci.org/pdf.php3?id=1109cholesterolginsengrathemogram
spellingShingle Deniz Uluışık
Ercan Keskin
The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet
Eurasian Journal of Veterinary Sciences
cholesterol
ginseng
rat
hemogram
title The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet
title_full The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet
title_fullStr The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet
title_full_unstemmed The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet
title_short The effect of ginseng on some hematological parameters in rats fed cholesterol-rich diet
title_sort effect of ginseng on some hematological parameters in rats fed cholesterol rich diet
topic cholesterol
ginseng
rat
hemogram
url http://eurasianjvetsci.org/pdf.php3?id=1109
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AT ercankeskin effectofginsengonsomehematologicalparametersinratsfedcholesterolrichdiet