[EMIM]AlCl4-ionic liquid catalyzed mechanochemically assisted green approach towards the synthesis of quinoxaline, 6H-indolo[2,3-b]quinoxaline and benzimidazole derivatives
In the presented work, a convenient and effective methodology for the synthesis of quinoxaline, 6H-indolo[2,3-b]quinoxaline and benzimidazole derivatives has been developed. The reaction of 1,2-diamines with various substituted benzil, isatin and aldehydes produces quinoxaline, 6H-indolo[2,3-b]quino...
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| Main Authors: | , , , , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2024-12-01
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| Series: | Results in Chemistry |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2211715624005800 |
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| Summary: | In the presented work, a convenient and effective methodology for the synthesis of quinoxaline, 6H-indolo[2,3-b]quinoxaline and benzimidazole derivatives has been developed. The reaction of 1,2-diamines with various substituted benzil, isatin and aldehydes produces quinoxaline, 6H-indolo[2,3-b]quinoxaline and benzimidazole derivatives respectively. The reaction between 1,2-diamines with various substituted benzils, isatins and aldehydes was carried out in presence of catalytic amount of [EMIM]AlCl4 (1-ethyl-3-methylimidazolium tetrachloroaluminate) ionic liquid in ethanol under the grinding condition in mortar and pestle. The ease of handling of catalyst, inclusion of eco-friendly solvent, attractive yield of the product, shorter reaction time and overall operational simplicity are some significant outcome of this procedure. |
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| ISSN: | 2211-7156 |