Plasma interleukin-27 (IL-27) levels are not modulated in patients with chronic HIV-1 infection.

Plasma interleukin-27 (IL-27) levels are not modulated in patients with chronic HIV-1 infection.

<h4>Objective</h4>IL-27 is an immunomodulatory cytokine with potent anti-HIV properties in PBMCs, CD4+ T cells, macrophages and immature dendritic cells. Previous smaller studies have suggested that HIV-1 infection may alter IL-27 and influence HIV-1 pathogenesis. The aim of this study w...

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Main Authors: Sanjay Swaminathan, Zonghui Hu, Adam W Rupert, Jeanette M Higgins, Robin L Dewar, Randy Stevens, Qian Chen, Catherine A Rehm, Julia A Metcalf, Michael W Baseler, H Clifford Lane, Tomozumi Imamichi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0098989
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