Short-Term Cardiac and Noncardiac Mortality Following Liver Transplantation

Objectives. To determine the importance of acute cardiac events as a cause of mortality compared to non-cardiac events in the four month period following liver transplantation (LT) using current preoperative cardiac screening strategies. Patients and Methods. We retrospectively reviewed timing, typ...

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Main Authors: Mackram F. Eleid, R. Todd Hurst, Hugo E. Vargas, Jorge Rakela, David C. Mulligan, Christopher P. Appleton
Format: Article
Language:English
Published: Wiley 2010-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2010/910165
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author Mackram F. Eleid
R. Todd Hurst
Hugo E. Vargas
Jorge Rakela
David C. Mulligan
Christopher P. Appleton
author_facet Mackram F. Eleid
R. Todd Hurst
Hugo E. Vargas
Jorge Rakela
David C. Mulligan
Christopher P. Appleton
author_sort Mackram F. Eleid
collection DOAJ
description Objectives. To determine the importance of acute cardiac events as a cause of mortality compared to non-cardiac events in the four month period following liver transplantation (LT) using current preoperative cardiac screening strategies. Patients and Methods. We retrospectively reviewed timing, type, and outcome of adverse cardiac events, and all cause mortality in the 4 month postoperative period in 393 consecutive LT patients from October 1999 to February 2008. Results. Of 30 total deaths (7.6% overall mortality rate), 27 (90%) were due to surgical or medical complications and 3 (10%) were primary cardiac deaths (0.8% cardiac mortality rate). Acute cardiac events occurred in 26 patients (6.6%), including 13 arrhythmias (50%), 7 new onset heart failures (27%), and 6 myocardial infarctions (23%). Twelve of 13 intraoperative events were arrhythmias (92%) including two of three cardiac deaths. Conclusions. Using current preoperative screening recommendations, deaths from primary cardiac events within four months of LT are very uncommon (0.8%), especially compared with deaths related to medical and surgical complications (6.9%).
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series Journal of Transplantation
spelling doaj-art-a99d010399334861ade9530ae0274a1e2025-02-03T01:23:58ZengWileyJournal of Transplantation2090-00072090-00152010-01-01201010.1155/2010/910165910165Short-Term Cardiac and Noncardiac Mortality Following Liver TransplantationMackram F. Eleid0R. Todd Hurst1Hugo E. Vargas2Jorge Rakela3David C. Mulligan4Christopher P. Appleton5Department of Internal Medicine, Mayo Clinic, Scottsdale, AZ 85259, USADivision of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Scottsdale, AZ 85259, USADivision of Hepatology, Department of Internal Medicine, Mayo Clinic, Scottsdale, AZ 85259, USADivision of Hepatology, Department of Internal Medicine, Mayo Clinic, Scottsdale, AZ 85259, USADivision of Transplant Surgery, Department of Internal Medicine, Mayo Clinic, Scottsdale, AZ 85259, USADivision of Cardiovascular Diseases, Department of Internal Medicine, Mayo Clinic, Scottsdale, AZ 85259, USAObjectives. To determine the importance of acute cardiac events as a cause of mortality compared to non-cardiac events in the four month period following liver transplantation (LT) using current preoperative cardiac screening strategies. Patients and Methods. We retrospectively reviewed timing, type, and outcome of adverse cardiac events, and all cause mortality in the 4 month postoperative period in 393 consecutive LT patients from October 1999 to February 2008. Results. Of 30 total deaths (7.6% overall mortality rate), 27 (90%) were due to surgical or medical complications and 3 (10%) were primary cardiac deaths (0.8% cardiac mortality rate). Acute cardiac events occurred in 26 patients (6.6%), including 13 arrhythmias (50%), 7 new onset heart failures (27%), and 6 myocardial infarctions (23%). Twelve of 13 intraoperative events were arrhythmias (92%) including two of three cardiac deaths. Conclusions. Using current preoperative screening recommendations, deaths from primary cardiac events within four months of LT are very uncommon (0.8%), especially compared with deaths related to medical and surgical complications (6.9%).http://dx.doi.org/10.1155/2010/910165
spellingShingle Mackram F. Eleid
R. Todd Hurst
Hugo E. Vargas
Jorge Rakela
David C. Mulligan
Christopher P. Appleton
Short-Term Cardiac and Noncardiac Mortality Following Liver Transplantation
Journal of Transplantation
title Short-Term Cardiac and Noncardiac Mortality Following Liver Transplantation
title_full Short-Term Cardiac and Noncardiac Mortality Following Liver Transplantation
title_fullStr Short-Term Cardiac and Noncardiac Mortality Following Liver Transplantation
title_full_unstemmed Short-Term Cardiac and Noncardiac Mortality Following Liver Transplantation
title_short Short-Term Cardiac and Noncardiac Mortality Following Liver Transplantation
title_sort short term cardiac and noncardiac mortality following liver transplantation
url http://dx.doi.org/10.1155/2010/910165
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