Quantification of 5-Methylcytosine in DNA by the Chloroacetaldehyde Reaction

The study of changes in genome-wide levels of DNA methylation has become a key focus for understanding the epigenetic regulation of gene expression. Many procedures exist to study DNA methylation, falling into two categories: gene-specific and genome-wide. Genome-wide methylation analysis is best pe...

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Bibliographic Details
Main Authors: Edward J. Oakeley, Frédéric Schmitt, Jean-Pierre Jost
Format: Article
Language:English
Published: Taylor & Francis Group 1999-10-01
Series:BioTechniques
Online Access:https://www.future-science.com/doi/10.2144/99274st05
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