Synovial Sarcoma of the Hand
The incidence of synovial sarcoma is 1.548 per 1,000,000. Synovial sarcoma localized to the palmar surface should, therefore, be considered extremely rare. This report documents a 34-year-old male with a right hand mass that had been present for a few years, continuing to grow in size. The mass was...
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Wiley
2020-01-01
|
| Series: | Case Reports in Pathology |
| Online Access: | http://dx.doi.org/10.1155/2020/8491864 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
| _version_ | 1832567469304184832 |
|---|---|
| author | Hovsep Ohan Greg Minassian Asaad H. Samra Matthew J. Zdilla |
| author_facet | Hovsep Ohan Greg Minassian Asaad H. Samra Matthew J. Zdilla |
| author_sort | Hovsep Ohan |
| collection | DOAJ |
| description | The incidence of synovial sarcoma is 1.548 per 1,000,000. Synovial sarcoma localized to the palmar surface should, therefore, be considered extremely rare. This report documents a 34-year-old male with a right hand mass that had been present for a few years, continuing to grow in size. The mass was located at the palm and extended from the mid-third metacarpal to involve all digits except the thumb. The mass was determined to be monophasic synovial sarcoma on histopathologic exam. Fluorescence in situ hybridization for SYT gene rearrangement was positive in 72% of cells. Resection of the mass was followed by radiation and chemotherapy. The patient had a long-term follow-up of 3.5 years with no evidence of any local recurrence of the tumor. This report increases awareness of this extremely rare malignancy—an awareness that is crucial for early diagnosis and improved survival rates. It is more common at younger ages but it can occur at any age, so it should be suspected and included in the differential diagnosis, especially when evaluating slow growing, nonresolving hand lesions. |
| format | Article |
| id | doaj-art-a980d9407e644de28fb75da80bfa5d9a |
| institution | Kabale University |
| issn | 2090-6781 2090-679X |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Pathology |
| spelling | doaj-art-a980d9407e644de28fb75da80bfa5d9a2025-02-03T01:01:27ZengWileyCase Reports in Pathology2090-67812090-679X2020-01-01202010.1155/2020/84918648491864Synovial Sarcoma of the HandHovsep Ohan0Greg Minassian1Asaad H. Samra2Matthew J. Zdilla3Department of Pathology, Anatomy and Laboratory Medicine (PALM), Robert C. Byrd Health Sciences Center, West Virginia University School of Medicine, Morgantown, West Virginia, USARutgers New Jersey Medical School, Newark, New Jersey, USAHackensack Meridian Health, Holmdel, New Jersey, USADepartment of Pathology, Anatomy and Laboratory Medicine (PALM), Robert C. Byrd Health Sciences Center, West Virginia University School of Medicine, Morgantown, West Virginia, USAThe incidence of synovial sarcoma is 1.548 per 1,000,000. Synovial sarcoma localized to the palmar surface should, therefore, be considered extremely rare. This report documents a 34-year-old male with a right hand mass that had been present for a few years, continuing to grow in size. The mass was located at the palm and extended from the mid-third metacarpal to involve all digits except the thumb. The mass was determined to be monophasic synovial sarcoma on histopathologic exam. Fluorescence in situ hybridization for SYT gene rearrangement was positive in 72% of cells. Resection of the mass was followed by radiation and chemotherapy. The patient had a long-term follow-up of 3.5 years with no evidence of any local recurrence of the tumor. This report increases awareness of this extremely rare malignancy—an awareness that is crucial for early diagnosis and improved survival rates. It is more common at younger ages but it can occur at any age, so it should be suspected and included in the differential diagnosis, especially when evaluating slow growing, nonresolving hand lesions.http://dx.doi.org/10.1155/2020/8491864 |
| spellingShingle | Hovsep Ohan Greg Minassian Asaad H. Samra Matthew J. Zdilla Synovial Sarcoma of the Hand Case Reports in Pathology |
| title | Synovial Sarcoma of the Hand |
| title_full | Synovial Sarcoma of the Hand |
| title_fullStr | Synovial Sarcoma of the Hand |
| title_full_unstemmed | Synovial Sarcoma of the Hand |
| title_short | Synovial Sarcoma of the Hand |
| title_sort | synovial sarcoma of the hand |
| url | http://dx.doi.org/10.1155/2020/8491864 |
| work_keys_str_mv | AT hovsepohan synovialsarcomaofthehand AT gregminassian synovialsarcomaofthehand AT asaadhsamra synovialsarcomaofthehand AT matthewjzdilla synovialsarcomaofthehand |