Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review
Conclusions: This report has the largest number of patients so far with PI and pneumoperitoneum after LT. These conditions have a high rejection and high mortality rate. Mechanical ventilation, tracheostomy, gastrointestinal procedure, CMV infection, Clostridium difficile (C. difficile) infection, a...
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Format: | Article |
Language: | English |
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Wiley
2024-01-01
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Series: | Journal of Transplantation |
Online Access: | http://dx.doi.org/10.1155/2024/8867932 |
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author | Hiroshi Kagawa Masashi Furukawa Ernest G. Chan Matthew Morrell Pablo G. Sanchez |
author_facet | Hiroshi Kagawa Masashi Furukawa Ernest G. Chan Matthew Morrell Pablo G. Sanchez |
author_sort | Hiroshi Kagawa |
collection | DOAJ |
description | Conclusions: This report has the largest number of patients so far with PI and pneumoperitoneum after LT. These conditions have a high rejection and high mortality rate. Mechanical ventilation, tracheostomy, gastrointestinal procedure, CMV infection, Clostridium difficile (C. difficile) infection, and immunosuppression can be the risk factors, and the management includes laparotomy or conservative management. It is generally recommended to proceed with laparotomy if patients have portal venous gas, elevated white blood cell count, elevated lactic acid level, decreased bicarbonate level, elevated amylase level, metabolic acidosis, abdominal tenderness, or abdominal distension. Otherwise, most of the patients recover with conservative management with nil per os (NPO), metronidazole, ganciclovir, antibiotics, high-flow oxygen, and holding mycophenolate mofetil (MMF). |
format | Article |
id | doaj-art-a97635a4d91849c6863e5b0bd903a4ae |
institution | Kabale University |
issn | 2090-0015 |
language | English |
publishDate | 2024-01-01 |
publisher | Wiley |
record_format | Article |
series | Journal of Transplantation |
spelling | doaj-art-a97635a4d91849c6863e5b0bd903a4ae2025-02-03T06:47:10ZengWileyJournal of Transplantation2090-00152024-01-01202410.1155/2024/8867932Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic ReviewHiroshi Kagawa0Masashi Furukawa1Ernest G. Chan2Matthew Morrell3Pablo G. Sanchez4Department of Cardiothoracic SurgeryDepartment of Cardiothoracic SurgeryDepartment of Cardiothoracic SurgeryDivision of PulmonaryDepartment of Cardiothoracic SurgeryConclusions: This report has the largest number of patients so far with PI and pneumoperitoneum after LT. These conditions have a high rejection and high mortality rate. Mechanical ventilation, tracheostomy, gastrointestinal procedure, CMV infection, Clostridium difficile (C. difficile) infection, and immunosuppression can be the risk factors, and the management includes laparotomy or conservative management. It is generally recommended to proceed with laparotomy if patients have portal venous gas, elevated white blood cell count, elevated lactic acid level, decreased bicarbonate level, elevated amylase level, metabolic acidosis, abdominal tenderness, or abdominal distension. Otherwise, most of the patients recover with conservative management with nil per os (NPO), metronidazole, ganciclovir, antibiotics, high-flow oxygen, and holding mycophenolate mofetil (MMF).http://dx.doi.org/10.1155/2024/8867932 |
spellingShingle | Hiroshi Kagawa Masashi Furukawa Ernest G. Chan Matthew Morrell Pablo G. Sanchez Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review Journal of Transplantation |
title | Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review |
title_full | Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review |
title_fullStr | Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review |
title_full_unstemmed | Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review |
title_short | Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review |
title_sort | pneumatosis intestinalis and pneumoperitoneum after lung transplantation single center experience and systematic review |
url | http://dx.doi.org/10.1155/2024/8867932 |
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