Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review

Conclusions: This report has the largest number of patients so far with PI and pneumoperitoneum after LT. These conditions have a high rejection and high mortality rate. Mechanical ventilation, tracheostomy, gastrointestinal procedure, CMV infection, Clostridium difficile (C. difficile) infection, a...

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Main Authors: Hiroshi Kagawa, Masashi Furukawa, Ernest G. Chan, Matthew Morrell, Pablo G. Sanchez
Format: Article
Language:English
Published: Wiley 2024-01-01
Series:Journal of Transplantation
Online Access:http://dx.doi.org/10.1155/2024/8867932
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author Hiroshi Kagawa
Masashi Furukawa
Ernest G. Chan
Matthew Morrell
Pablo G. Sanchez
author_facet Hiroshi Kagawa
Masashi Furukawa
Ernest G. Chan
Matthew Morrell
Pablo G. Sanchez
author_sort Hiroshi Kagawa
collection DOAJ
description Conclusions: This report has the largest number of patients so far with PI and pneumoperitoneum after LT. These conditions have a high rejection and high mortality rate. Mechanical ventilation, tracheostomy, gastrointestinal procedure, CMV infection, Clostridium difficile (C. difficile) infection, and immunosuppression can be the risk factors, and the management includes laparotomy or conservative management. It is generally recommended to proceed with laparotomy if patients have portal venous gas, elevated white blood cell count, elevated lactic acid level, decreased bicarbonate level, elevated amylase level, metabolic acidosis, abdominal tenderness, or abdominal distension. Otherwise, most of the patients recover with conservative management with nil per os (NPO), metronidazole, ganciclovir, antibiotics, high-flow oxygen, and holding mycophenolate mofetil (MMF).
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institution Kabale University
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publishDate 2024-01-01
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series Journal of Transplantation
spelling doaj-art-a97635a4d91849c6863e5b0bd903a4ae2025-02-03T06:47:10ZengWileyJournal of Transplantation2090-00152024-01-01202410.1155/2024/8867932Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic ReviewHiroshi Kagawa0Masashi Furukawa1Ernest G. Chan2Matthew Morrell3Pablo G. Sanchez4Department of Cardiothoracic SurgeryDepartment of Cardiothoracic SurgeryDepartment of Cardiothoracic SurgeryDivision of PulmonaryDepartment of Cardiothoracic SurgeryConclusions: This report has the largest number of patients so far with PI and pneumoperitoneum after LT. These conditions have a high rejection and high mortality rate. Mechanical ventilation, tracheostomy, gastrointestinal procedure, CMV infection, Clostridium difficile (C. difficile) infection, and immunosuppression can be the risk factors, and the management includes laparotomy or conservative management. It is generally recommended to proceed with laparotomy if patients have portal venous gas, elevated white blood cell count, elevated lactic acid level, decreased bicarbonate level, elevated amylase level, metabolic acidosis, abdominal tenderness, or abdominal distension. Otherwise, most of the patients recover with conservative management with nil per os (NPO), metronidazole, ganciclovir, antibiotics, high-flow oxygen, and holding mycophenolate mofetil (MMF).http://dx.doi.org/10.1155/2024/8867932
spellingShingle Hiroshi Kagawa
Masashi Furukawa
Ernest G. Chan
Matthew Morrell
Pablo G. Sanchez
Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review
Journal of Transplantation
title Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review
title_full Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review
title_fullStr Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review
title_full_unstemmed Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review
title_short Pneumatosis Intestinalis and Pneumoperitoneum After Lung Transplantation: Single-Center Experience and Systematic Review
title_sort pneumatosis intestinalis and pneumoperitoneum after lung transplantation single center experience and systematic review
url http://dx.doi.org/10.1155/2024/8867932
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