An Observational Study on The Role of Magnetic Resonance Imaging in The Evaluation of Soft Tissue Tumors with Histopathological Correlation at Tertiary Care Centre
Background: The primary aim of this study is to evaluate the role of magnetic resonance imaging (MRI) in the assessment of soft tissue tumors with histopathological correlation at a tertiary care center. Methods: An observational study was conducted on 75 patients (n = 75) in the Department of Radi...
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Tehran University of Medical Sciences
2024-10-01
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| Series: | Health Technology Assessment in Action |
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| Online Access: | https://htainaction.tums.ac.ir/index.php/hta/article/view/256 |
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| author | Sriramula Sripriya Tejaswini Mogalagunta Sunitha Bajaj Sudha Bindu T Madhavi T |
| author_facet | Sriramula Sripriya Tejaswini Mogalagunta Sunitha Bajaj Sudha Bindu T Madhavi T |
| author_sort | Sriramula Sripriya |
| collection | DOAJ |
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Background: The primary aim of this study is to evaluate the role of magnetic resonance imaging (MRI) in the assessment of soft tissue tumors with histopathological correlation at a tertiary care center.
Methods: An observational study was conducted on 75 patients (n = 75) in the Department of Radiodiagnosis over 18 months. The targeted population comprised patients who presented to the Radiodiagnosis Department for radiological imaging of soft tissue tumors.
Results: Out of 75 cases, 20% were found to have benign tumors, while 80% were found to have malignant tumors. The most frequent benign tumor was fibromatosis, with n = 10 cases (13.33%), and the most common malignant tumor was synovial sarcoma, with n = 14 cases (18.66%). The benign age group ranged from 11 to 20 years. T2-weighted heterogeneous hyperintensity was noted more frequently in malignant lesions, demonstrating a high positive predictive value; that is, 83% of malignant tumors exhibited changes on diffusion-weighted imaging/ apparent diffusion co efficient (DWI/ADC). Low-grade malignant lesions showed no restrictions. Most benign lesions displayed restrictions, with a high positive predictive value of 98.14%, specificity of 93.33%, and sensitivity of 88.33%.
Conclusions: Soft tissue tumors can be detected and locally staged using MRI; thus, this technique has proven its value. Intralesional hemorrhage and calcification are two parameters that have been shown to have no substantial association with cancer. Due to its high sensitivity, MRI is a viable option for evaluating soft tissue tumors.
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| format | Article |
| id | doaj-art-a9528cf529324f79830e9afab8c2eb8d |
| institution | OA Journals |
| issn | 2645-3835 |
| language | English |
| publishDate | 2024-10-01 |
| publisher | Tehran University of Medical Sciences |
| record_format | Article |
| series | Health Technology Assessment in Action |
| spelling | doaj-art-a9528cf529324f79830e9afab8c2eb8d2025-08-20T02:14:02ZengTehran University of Medical SciencesHealth Technology Assessment in Action2645-38352024-10-0184An Observational Study on The Role of Magnetic Resonance Imaging in The Evaluation of Soft Tissue Tumors with Histopathological Correlation at Tertiary Care CentreSriramula Sripriya0Tejaswini Mogalagunta1Sunitha Bajaj2Sudha Bindu T3Madhavi T4MBBS, MD Radio-diagnosis, Junior resident at Department of Radio-diagnosis from Osmania Medical College, Hyderabad, IndiaMBBS, MD Radio-diagnosis, Junior resident at Department of Radio-diagnosis from Osmania Medical College, Hyderabad, IndiaMBBS, MD, DNB Radio-diagnosis, Professor and HOD at Department of Radio-diagnosis from Osmania Medical College, Hyderabad, IndiaMBBS , MD Radio-diagnosis ,Professor at Department of Radio-diagnosis from Osmania Medical College, Hyderabad, IndiaMBBS, MD Radio-diagnosis, Assistant Professor at Department of Radio-diagnosis from MNJ Institute of Oncology and Regional Cancer Centre, Hyderabad, India Background: The primary aim of this study is to evaluate the role of magnetic resonance imaging (MRI) in the assessment of soft tissue tumors with histopathological correlation at a tertiary care center. Methods: An observational study was conducted on 75 patients (n = 75) in the Department of Radiodiagnosis over 18 months. The targeted population comprised patients who presented to the Radiodiagnosis Department for radiological imaging of soft tissue tumors. Results: Out of 75 cases, 20% were found to have benign tumors, while 80% were found to have malignant tumors. The most frequent benign tumor was fibromatosis, with n = 10 cases (13.33%), and the most common malignant tumor was synovial sarcoma, with n = 14 cases (18.66%). The benign age group ranged from 11 to 20 years. T2-weighted heterogeneous hyperintensity was noted more frequently in malignant lesions, demonstrating a high positive predictive value; that is, 83% of malignant tumors exhibited changes on diffusion-weighted imaging/ apparent diffusion co efficient (DWI/ADC). Low-grade malignant lesions showed no restrictions. Most benign lesions displayed restrictions, with a high positive predictive value of 98.14%, specificity of 93.33%, and sensitivity of 88.33%. Conclusions: Soft tissue tumors can be detected and locally staged using MRI; thus, this technique has proven its value. Intralesional hemorrhage and calcification are two parameters that have been shown to have no substantial association with cancer. Due to its high sensitivity, MRI is a viable option for evaluating soft tissue tumors. https://htainaction.tums.ac.ir/index.php/hta/article/view/256MRISoft-tissue tumoursRadiologyComputed tomography |
| spellingShingle | Sriramula Sripriya Tejaswini Mogalagunta Sunitha Bajaj Sudha Bindu T Madhavi T An Observational Study on The Role of Magnetic Resonance Imaging in The Evaluation of Soft Tissue Tumors with Histopathological Correlation at Tertiary Care Centre Health Technology Assessment in Action MRI Soft-tissue tumours Radiology Computed tomography |
| title | An Observational Study on The Role of Magnetic Resonance Imaging in The Evaluation of Soft Tissue Tumors with Histopathological Correlation at Tertiary Care Centre |
| title_full | An Observational Study on The Role of Magnetic Resonance Imaging in The Evaluation of Soft Tissue Tumors with Histopathological Correlation at Tertiary Care Centre |
| title_fullStr | An Observational Study on The Role of Magnetic Resonance Imaging in The Evaluation of Soft Tissue Tumors with Histopathological Correlation at Tertiary Care Centre |
| title_full_unstemmed | An Observational Study on The Role of Magnetic Resonance Imaging in The Evaluation of Soft Tissue Tumors with Histopathological Correlation at Tertiary Care Centre |
| title_short | An Observational Study on The Role of Magnetic Resonance Imaging in The Evaluation of Soft Tissue Tumors with Histopathological Correlation at Tertiary Care Centre |
| title_sort | observational study on the role of magnetic resonance imaging in the evaluation of soft tissue tumors with histopathological correlation at tertiary care centre |
| topic | MRI Soft-tissue tumours Radiology Computed tomography |
| url | https://htainaction.tums.ac.ir/index.php/hta/article/view/256 |
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