Clinical Effects of Topical Tacrolimus on Fox-Fordyce Disease
Fox-Fordyce Disease (FFD) is a rare, chronic, pruritic, inflammatory disorder of apocrine glands. It is characterized by dome-shaped, firm, discrete, skin-colored, and monomorphic perifollicular papules. The most common sites of involvement are axillae and anogenital and periareolar regions which ar...
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| Format: | Article |
| Language: | English |
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Wiley
2015-01-01
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| Series: | Case Reports in Dermatological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2015/205418 |
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| author | Hilal Kaya Erdoğan Işıl Bulur Zeliha Kaya |
| author_facet | Hilal Kaya Erdoğan Işıl Bulur Zeliha Kaya |
| author_sort | Hilal Kaya Erdoğan |
| collection | DOAJ |
| description | Fox-Fordyce Disease (FFD) is a rare, chronic, pruritic, inflammatory disorder of apocrine glands. It is characterized by dome-shaped, firm, discrete, skin-colored, and monomorphic perifollicular papules. The most common sites of involvement are axillae and anogenital and periareolar regions which are rich in apocrine sweat glands. Treatment is difficult. Topical, intralesional steroids, topical tretinoin, adapalene, clindamycin, benzoyl peroxide, oral contraceptives, isotretinoin, phototherapy, electrocauterisation, excision-liposuction and curettage, and fractional carbon dioxide laser are among the treatment options. In the literature, there are articles reporting beneficial effects of pimecrolimus in FFD. Nevertheless, there have not been any reports about the use of tacrolimus in FFD. We report two patients diagnosed with FFD by clinical and histopathologic examination and discussed therapeutic effects of topical tacrolimus on FFD in the light of literature. |
| format | Article |
| id | doaj-art-a94dc3266b3145c58b28cdb2df47d8c8 |
| institution | Kabale University |
| issn | 2090-6463 2090-6471 |
| language | English |
| publishDate | 2015-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Dermatological Medicine |
| spelling | doaj-art-a94dc3266b3145c58b28cdb2df47d8c82025-02-03T06:01:28ZengWileyCase Reports in Dermatological Medicine2090-64632090-64712015-01-01201510.1155/2015/205418205418Clinical Effects of Topical Tacrolimus on Fox-Fordyce DiseaseHilal Kaya Erdoğan0Işıl Bulur1Zeliha Kaya2Department of Dermatology, Eskisehir Osmangazi University, 26480 Eskisehir, TurkeyDepartment of Dermatology, Eskisehir Osmangazi University, 26480 Eskisehir, TurkeyDepartment of Pathology, Kırsehir Ahi Evran University, 40200 Kirsehir, TurkeyFox-Fordyce Disease (FFD) is a rare, chronic, pruritic, inflammatory disorder of apocrine glands. It is characterized by dome-shaped, firm, discrete, skin-colored, and monomorphic perifollicular papules. The most common sites of involvement are axillae and anogenital and periareolar regions which are rich in apocrine sweat glands. Treatment is difficult. Topical, intralesional steroids, topical tretinoin, adapalene, clindamycin, benzoyl peroxide, oral contraceptives, isotretinoin, phototherapy, electrocauterisation, excision-liposuction and curettage, and fractional carbon dioxide laser are among the treatment options. In the literature, there are articles reporting beneficial effects of pimecrolimus in FFD. Nevertheless, there have not been any reports about the use of tacrolimus in FFD. We report two patients diagnosed with FFD by clinical and histopathologic examination and discussed therapeutic effects of topical tacrolimus on FFD in the light of literature.http://dx.doi.org/10.1155/2015/205418 |
| spellingShingle | Hilal Kaya Erdoğan Işıl Bulur Zeliha Kaya Clinical Effects of Topical Tacrolimus on Fox-Fordyce Disease Case Reports in Dermatological Medicine |
| title | Clinical Effects of Topical Tacrolimus on Fox-Fordyce Disease |
| title_full | Clinical Effects of Topical Tacrolimus on Fox-Fordyce Disease |
| title_fullStr | Clinical Effects of Topical Tacrolimus on Fox-Fordyce Disease |
| title_full_unstemmed | Clinical Effects of Topical Tacrolimus on Fox-Fordyce Disease |
| title_short | Clinical Effects of Topical Tacrolimus on Fox-Fordyce Disease |
| title_sort | clinical effects of topical tacrolimus on fox fordyce disease |
| url | http://dx.doi.org/10.1155/2015/205418 |
| work_keys_str_mv | AT hilalkayaerdogan clinicaleffectsoftopicaltacrolimusonfoxfordycedisease AT isılbulur clinicaleffectsoftopicaltacrolimusonfoxfordycedisease AT zelihakaya clinicaleffectsoftopicaltacrolimusonfoxfordycedisease |