Solubility and Dissolution Rate Determination of Different Antiretroviral Drugs in Different pH Media Using UV Visible Spectrophotometer

Solubility and dissolution rate of three antiretroviral drugs such as lamivudine, zidovudine and stavudine was studied in four media having different pH. The samples were analyzed by using UV Visible spectrophotometer. lamivudine shows more solubility that is 276.08 mg/mL in 0.01 N HCl. Stavudine s...

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Bibliographic Details
Main Authors: K. Prakash, P. Narayana Raju, K. Shanta Kumari, M. Lakshmi Narasu
Format: Article
Language:English
Published: Wiley 2008-01-01
Series:E-Journal of Chemistry
Online Access:http://dx.doi.org/10.1155/2008/125917
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