Bilateral Germ Cell Tumor of the Testis: Biological and Clinical Implications for a Stem Versus Genetic Origin of Cancers

Bilateral Germ Cell Tumor of the Testis: Biological and Clinical Implications for a Stem Versus Genetic Origin of Cancers

Germ cell tumors of the testis (GCTs) provide an ideal tumor model to investigate the cellular versus genetic origin of cancers. In this single institutional study, we evaluated 38 patients with bilateral GCT, including tumors that occurred simultaneously (synchronous) and those occurring at differe...

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Bibliographic Details
Main Authors: Jamaal C. Jackson, Darren Sanchez, Aron Y. Joon, Marcos R. Estecio, Andrew C. Johns, Amishi Y. Shah, Matthew Campbell, John F. Ward, Louis L. Pisters, Charles C. Guo, Miao Zhang, Niki M. Zacharias, Shi-Ming Tu
Format: Article
Language:English
Published: MDPI AG 2025-04-01
Series:Cells
Subjects:
bilateral testicular cancer
cancer stem cells
origin of cancers
tumor heterogeneity
Online Access:https://www.mdpi.com/2073-4409/14/9/658
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