A transcriptomic and proteomic analysis and comparison of human brain tissue from patients with and without epilepsy

A transcriptomic and proteomic analysis and comparison of human brain tissue from patients with and without epilepsy

Abstract The present study was to investigate potential biomarkers and therapeutic targets for epilepsy by conducting a transcriptomic and proteomic analysis of human brain tissue from patients with epileptic lesions. Brain tissue was collected from the epileptic lesions after surgical resection and...

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Main Authors: Taiyang Zhu, Yan Zhou, Lei Zhang, Lingwen Kong, Hai Tang, Qihua Xiao, Xiaoyu Sun, Fanyu Shen, Hui Zhou, Wanyan Ni, Sha Liu, Huimin Gao, Guoliang Jin, Xiao Jia, Fang Hua
Format: Article
Language:English
Published: Nature Portfolio 2025-05-01
Series:Scientific Reports
Subjects:
Epilepsy
Multi-omics analysis
TPPP3
PCSK1
DPYSL3
Online Access:https://doi.org/10.1038/s41598-025-00986-4
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