Robust intrapulmonary CD8 T cell responses and protection with an attenuated N1L deleted vaccinia virus.
<h4>Background</h4>Vaccinia viruses have been used as a model for viral disease and as a protective live vaccine.<h4>Methodology and principal findings</h4>We investigated the immunogenicity of an attenuated strain of vaccinia virus engineered to inactivate the N1L gene (vGK5...
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| Main Authors: | Anuja Mathew, Joel O'Bryan, William Marshall, Girish J Kotwal, Masanori Terajima, Sharone Green, Alan L Rothman, Francis A Ennis |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Public Library of Science (PLoS)
2008-10-01
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| Series: | PLoS ONE |
| Online Access: | https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0003323&type=printable |
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