Stent Thrombosis Patients with Hyporesponsiveness to Clopidogrel, Prasugrel, and Ticagrelor: A Case Series Using Short Thromboelastography
Patients after percutaneous coronary intervention (PCI) with stent implantation and functional hyporesponsiveness to P2Y12 inhibitors are at higher risk of ischaemic events, particularly stent thrombosis (ST). It is currently not routine practice to assess the functional response to these agents. Ho...
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| Format: | Article |
| Language: | English |
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Wiley
2016-01-01
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| Series: | Case Reports in Medicine |
| Online Access: | http://dx.doi.org/10.1155/2016/2096181 |
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| author | Bartosz Olechowski Alexander Ashby Nalyaka Sambu Michael Mahmoudi Nick Curzen |
| author_facet | Bartosz Olechowski Alexander Ashby Nalyaka Sambu Michael Mahmoudi Nick Curzen |
| author_sort | Bartosz Olechowski |
| collection | DOAJ |
| description | Patients after percutaneous coronary intervention (PCI) with stent implantation and functional hyporesponsiveness to P2Y12 inhibitors are at higher risk of ischaemic events, particularly stent thrombosis (ST). It is currently not routine practice to assess the functional response to these agents. However, concern over functional hyporesponsiveness to clopidogrel has led to widespread uptake of prasugrel and ticagrelor as the default P2Y12 inhibitor after stent implantation in patients with acute coronary syndrome. Here we report, for the first time, 3 cases in which patients who have had ST exhibit hyporesponsiveness to clopidogrel, prasugrel, and ticagrelor. |
| format | Article |
| id | doaj-art-a9276fe141c241e69910a01415dbb608 |
| institution | Kabale University |
| issn | 1687-9627 1687-9635 |
| language | English |
| publishDate | 2016-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Medicine |
| spelling | doaj-art-a9276fe141c241e69910a01415dbb6082025-02-03T05:50:16ZengWileyCase Reports in Medicine1687-96271687-96352016-01-01201610.1155/2016/20961812096181Stent Thrombosis Patients with Hyporesponsiveness to Clopidogrel, Prasugrel, and Ticagrelor: A Case Series Using Short ThromboelastographyBartosz Olechowski0Alexander Ashby1Nalyaka Sambu2Michael Mahmoudi3Nick Curzen4Wessex Cardiothoracic Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UKWessex Cardiothoracic Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UKWessex Cardiothoracic Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UKWessex Cardiothoracic Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UKWessex Cardiothoracic Centre, University Hospital Southampton NHS Foundation Trust, Southampton, UKPatients after percutaneous coronary intervention (PCI) with stent implantation and functional hyporesponsiveness to P2Y12 inhibitors are at higher risk of ischaemic events, particularly stent thrombosis (ST). It is currently not routine practice to assess the functional response to these agents. However, concern over functional hyporesponsiveness to clopidogrel has led to widespread uptake of prasugrel and ticagrelor as the default P2Y12 inhibitor after stent implantation in patients with acute coronary syndrome. Here we report, for the first time, 3 cases in which patients who have had ST exhibit hyporesponsiveness to clopidogrel, prasugrel, and ticagrelor.http://dx.doi.org/10.1155/2016/2096181 |
| spellingShingle | Bartosz Olechowski Alexander Ashby Nalyaka Sambu Michael Mahmoudi Nick Curzen Stent Thrombosis Patients with Hyporesponsiveness to Clopidogrel, Prasugrel, and Ticagrelor: A Case Series Using Short Thromboelastography Case Reports in Medicine |
| title | Stent Thrombosis Patients with Hyporesponsiveness to Clopidogrel, Prasugrel, and Ticagrelor: A Case Series Using Short Thromboelastography |
| title_full | Stent Thrombosis Patients with Hyporesponsiveness to Clopidogrel, Prasugrel, and Ticagrelor: A Case Series Using Short Thromboelastography |
| title_fullStr | Stent Thrombosis Patients with Hyporesponsiveness to Clopidogrel, Prasugrel, and Ticagrelor: A Case Series Using Short Thromboelastography |
| title_full_unstemmed | Stent Thrombosis Patients with Hyporesponsiveness to Clopidogrel, Prasugrel, and Ticagrelor: A Case Series Using Short Thromboelastography |
| title_short | Stent Thrombosis Patients with Hyporesponsiveness to Clopidogrel, Prasugrel, and Ticagrelor: A Case Series Using Short Thromboelastography |
| title_sort | stent thrombosis patients with hyporesponsiveness to clopidogrel prasugrel and ticagrelor a case series using short thromboelastography |
| url | http://dx.doi.org/10.1155/2016/2096181 |
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