Delirium and Associated Length of Stay and Costs in Critically Ill Patients

Purpose. Delirium frequently affects critically ill patients in the intensive care unit (ICU). The purpose of this study is to evaluate the impact of delirium on ICU and hospital length of stay (LOS) and perform a cost analysis. Materials and Methods. Prospective studies and randomized controlled tr...

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Main Authors: Claudia Dziegielewski, Charlenn Skead, Toros Canturk, Colleen Webber, Shannon M. Fernando, Laura H. Thompson, Madison Foster, Vanja Ristovic, Peter G. Lawlor, Dipayan Chaudhuri, Chintan Dave, Brent Herritt, Shirley H. Bush, Salmaan Kanji, Peter Tanuseputro, Kednapa Thavorn, Erin Rosenberg, Kwadwo Kyeremanteng
Format: Article
Language:English
Published: Wiley 2021-01-01
Series:Critical Care Research and Practice
Online Access:http://dx.doi.org/10.1155/2021/6612187
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author Claudia Dziegielewski
Charlenn Skead
Toros Canturk
Colleen Webber
Shannon M. Fernando
Laura H. Thompson
Madison Foster
Vanja Ristovic
Peter G. Lawlor
Dipayan Chaudhuri
Chintan Dave
Brent Herritt
Shirley H. Bush
Salmaan Kanji
Peter Tanuseputro
Kednapa Thavorn
Erin Rosenberg
Kwadwo Kyeremanteng
author_facet Claudia Dziegielewski
Charlenn Skead
Toros Canturk
Colleen Webber
Shannon M. Fernando
Laura H. Thompson
Madison Foster
Vanja Ristovic
Peter G. Lawlor
Dipayan Chaudhuri
Chintan Dave
Brent Herritt
Shirley H. Bush
Salmaan Kanji
Peter Tanuseputro
Kednapa Thavorn
Erin Rosenberg
Kwadwo Kyeremanteng
author_sort Claudia Dziegielewski
collection DOAJ
description Purpose. Delirium frequently affects critically ill patients in the intensive care unit (ICU). The purpose of this study is to evaluate the impact of delirium on ICU and hospital length of stay (LOS) and perform a cost analysis. Materials and Methods. Prospective studies and randomized controlled trials of patients in the ICU with delirium published between January 1, 2015, and December 31, 2020, were evaluated. Outcome variables including ICU and hospital LOS were obtained, and ICU and hospital costs were derived from the respective LOS. Results. Forty-one studies met inclusion criteria. The mean difference of ICU LOS between patients with and without delirium was significant at 4.77 days (p<0.001); for hospital LOS, this was significant at 6.67 days (p<0.001). Cost data were extractable for 27 studies in which both ICU and hospital LOS were available. The mean difference of ICU costs between patients with and without delirium was significant at $3,921 (p<0.001); for hospital costs, the mean difference was $5,936 (p<0.001). Conclusion. ICU and hospital LOS and associated costs were significantly higher for patients with delirium, compared to those without delirium. Further research is necessary to elucidate other determinants of increased costs and cost-reducing strategies for critically ill patients with delirium. This can provide insight into the required resources for the prevention of delirium, which may contribute to decreasing healthcare expenditure while optimizing the quality of care.
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spelling doaj-art-a927276877a1408dae1d87516e13cb982025-02-03T01:10:53ZengWileyCritical Care Research and Practice2090-13052090-13132021-01-01202110.1155/2021/66121876612187Delirium and Associated Length of Stay and Costs in Critically Ill PatientsClaudia Dziegielewski0Charlenn Skead1Toros Canturk2Colleen Webber3Shannon M. Fernando4Laura H. Thompson5Madison Foster6Vanja Ristovic7Peter G. Lawlor8Dipayan Chaudhuri9Chintan Dave10Brent Herritt11Shirley H. Bush12Salmaan Kanji13Peter Tanuseputro14Kednapa Thavorn15Erin Rosenberg16Kwadwo Kyeremanteng17Department of Medicine, University of Ottawa, Ottawa, ON, CanadaDepartment of Medicine, University of Ottawa, Ottawa, ON, CanadaDepartment of Medicine, University of Ottawa, Ottawa, ON, CanadaOttawa Hospital Research Institute, University of Ottawa, Ottawa, ON, CanadaDivision of Critical Care, Department of Medicine, University of Ottawa, Ottawa, ON, CanadaOttawa Hospital Research Institute, University of Ottawa, Ottawa, ON, CanadaOttawa Hospital Research Institute, University of Ottawa, Ottawa, ON, CanadaDepartment of Anesthesia, University of Ottawa, Ottawa, ON, CanadaOttawa Hospital Research Institute, University of Ottawa, Ottawa, ON, CanadaDivision of Critical Care, Department of Medicine, University of Ottawa, Ottawa, ON, CanadaDepartment of Medicine, University of Ottawa, Ottawa, ON, CanadaDivision of Critical Care, Department of Medicine, University of Ottawa, Ottawa, ON, CanadaOttawa Hospital Research Institute, University of Ottawa, Ottawa, ON, CanadaOttawa Hospital Research Institute, University of Ottawa, Ottawa, ON, CanadaBruyère Research Institute, Ottawa, ON, CanadaICES uOttawa, Ottawa, ON, CanadaDivision of Critical Care, Department of Medicine, University of Ottawa, Ottawa, ON, CanadaDivision of Critical Care, Department of Medicine, University of Ottawa, Ottawa, ON, CanadaPurpose. Delirium frequently affects critically ill patients in the intensive care unit (ICU). The purpose of this study is to evaluate the impact of delirium on ICU and hospital length of stay (LOS) and perform a cost analysis. Materials and Methods. Prospective studies and randomized controlled trials of patients in the ICU with delirium published between January 1, 2015, and December 31, 2020, were evaluated. Outcome variables including ICU and hospital LOS were obtained, and ICU and hospital costs were derived from the respective LOS. Results. Forty-one studies met inclusion criteria. The mean difference of ICU LOS between patients with and without delirium was significant at 4.77 days (p<0.001); for hospital LOS, this was significant at 6.67 days (p<0.001). Cost data were extractable for 27 studies in which both ICU and hospital LOS were available. The mean difference of ICU costs between patients with and without delirium was significant at $3,921 (p<0.001); for hospital costs, the mean difference was $5,936 (p<0.001). Conclusion. ICU and hospital LOS and associated costs were significantly higher for patients with delirium, compared to those without delirium. Further research is necessary to elucidate other determinants of increased costs and cost-reducing strategies for critically ill patients with delirium. This can provide insight into the required resources for the prevention of delirium, which may contribute to decreasing healthcare expenditure while optimizing the quality of care.http://dx.doi.org/10.1155/2021/6612187
spellingShingle Claudia Dziegielewski
Charlenn Skead
Toros Canturk
Colleen Webber
Shannon M. Fernando
Laura H. Thompson
Madison Foster
Vanja Ristovic
Peter G. Lawlor
Dipayan Chaudhuri
Chintan Dave
Brent Herritt
Shirley H. Bush
Salmaan Kanji
Peter Tanuseputro
Kednapa Thavorn
Erin Rosenberg
Kwadwo Kyeremanteng
Delirium and Associated Length of Stay and Costs in Critically Ill Patients
Critical Care Research and Practice
title Delirium and Associated Length of Stay and Costs in Critically Ill Patients
title_full Delirium and Associated Length of Stay and Costs in Critically Ill Patients
title_fullStr Delirium and Associated Length of Stay and Costs in Critically Ill Patients
title_full_unstemmed Delirium and Associated Length of Stay and Costs in Critically Ill Patients
title_short Delirium and Associated Length of Stay and Costs in Critically Ill Patients
title_sort delirium and associated length of stay and costs in critically ill patients
url http://dx.doi.org/10.1155/2021/6612187
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