Addressing genome scale design tradeoffs in Pseudomonas putida for bioconversion of an aromatic carbon source

Abstract Genome-scale metabolic models (GSMM) are commonly used to identify gene deletion sets that result in growth coupling and pairing product formation with substrate utilization and can improve strain performance beyond levels typically accessible using traditional strain engineering approaches...

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Bibliographic Details
Main Authors: Deepanwita Banerjee, Javier Menasalvas, Yan Chen, Jennifer W. Gin, Edward E. K. Baidoo, Christopher J. Petzold, Thomas Eng, Aindrila Mukhopadhyay
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:npj Systems Biology and Applications
Online Access:https://doi.org/10.1038/s41540-024-00480-z
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