Brachyury promotes proliferation and migration of colorectal cancer cells by targeting MMP14

Brachyury promotes proliferation and migration of colorectal cancer cells by targeting MMP14

Abstract Background The incidence and mortality rates of colorectal cancer (CRC) are rising, and it is the second most common cause of cancer-related deaths worldwide. Although the transcription factor, Brachyury is intricately linked with various clinical malignancies, the mechanisms by which it in...

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Bibliographic Details
Main Authors: Ming Chen, Huiheng Qu, Xiao Liang, Ying Huang, Zhengjie Yang, Pei Lu, Keqin Shi, Peng Chen, Yanjing Zhang, Hui Zhou, Jiazeng Xia, Jun Shen
Format: Article
Language:English
Published: BMC 2025-04-01
Series:Cancer Cell International
Subjects:
Brachyury
Colorectal cancer
MMP14
Proliferation
Migration
Online Access:https://doi.org/10.1186/s12935-025-03726-w
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