A high-fat meal significantly impacts the bioavailability and biphasic absorption of cannabidiol (CBD) from a CBD-rich extract in men and women

A high-fat meal significantly impacts the bioavailability and biphasic absorption of cannabidiol (CBD) from a CBD-rich extract in men and women

Abstract Cannabidiol (CBD), a specialized metabolite (phytocannabinoid) abundant in Cannabis sativa, is attracting increasing attention for its alleged health-promoting properties. The present study aimed to investigate the pharmacokinetics of CBD and its primary metabolite, 7‐hydroxy‐cannabidiol (7...

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Bibliographic Details
Main Authors: Bo Anne Daniëlla Frederique Saals, Tessa Helena De Bie, Eral Osmanoglou, Ties van de Laar, Adriaan Willem Tuin, Anne Claire Benedikte van Orten-Luiten, Renger Frederik Witkamp
Format: Article
Language:English
Published: Nature Portfolio 2025-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-025-87621-4
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