The critical role of TRIM protein family in intervertebral disc degeneration: mechanistic insights and therapeutic perspectives

Intervertebral disc degeneration (IVDD) is a leading cause of chronic back pain, contributing significantly to reduced quality of life and global public health burdens. The TRIM (Tripartite Motif-containing) protein family, with its diverse regulatory roles, has emerged as a key player in critical c...

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Bibliographic Details
Main Authors: Shangze Li, Wenli Jiang, Fei Chen, Jiao Qian, Jun Yang
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-02-01
Series:Frontiers in Cell and Developmental Biology
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Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2025.1525073/full
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