Risk prediction models for permanence of temporary stoma after radical surgery of rectal cancer: a systematic review

Abstract Objective To methodologically assess the prediction model for temporary stoma permanence in patients with rectal cancer and provide evidence-based guidance for the construction and clinical application of related models. Methods From launch to January 3, 2025, computer searches were perform...

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Main Authors: Wenjing Tan, Shiyin Cai, Juanqin Wu, Wenke Wu, Shan Wang, Yaqiu Li, Lulu Liu, Liping Tang, Ying Cao
Format: Article
Language:English
Published: BMC 2025-06-01
Series:World Journal of Surgical Oncology
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Online Access:https://doi.org/10.1186/s12957-025-03895-y
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author Wenjing Tan
Shiyin Cai
Juanqin Wu
Wenke Wu
Shan Wang
Yaqiu Li
Lulu Liu
Liping Tang
Ying Cao
author_facet Wenjing Tan
Shiyin Cai
Juanqin Wu
Wenke Wu
Shan Wang
Yaqiu Li
Lulu Liu
Liping Tang
Ying Cao
author_sort Wenjing Tan
collection DOAJ
description Abstract Objective To methodologically assess the prediction model for temporary stoma permanence in patients with rectal cancer and provide evidence-based guidance for the construction and clinical application of related models. Methods From launch to January 3, 2025, computer searches were performed in nine databases. Two researchers independently searched the literature, and the Critical Appraisal and Data Extraction Checklist for Systematic Evaluation of Predictive Modelling was used to extract data. The Predictive Modelling Research Risk of Bias Assessment Tool was used to assess the studies’ applicability and risk of bias. Results Nine studies were incorporated, exhibiting AUC/C-index values between 0.612 and 0.942, signifying good predictive efficacy in some models. Nonetheless, the included studies showed restricted applicability and a high risk of bias, especially regarding the selection of research populations and data analysis. The predominant determinants across models encompassed T-stage, neoadjuvant chemoradiotherapy, American Society of Anesthesiologists score, carcinoembryonic antigen level, distant metastasis, lymph node metastasis, anastomotic leakage, and age. Conclusion Current prediction models for temporary stoma permanence in rectal cancer patients exhibit significant limitations. In order to improve the accuracy of clinical predictions and inform clinical decision-making, future research should improve study design and reporting standards, as well as build and verify a prediction model that is highly applicable to real-world clinical demands and has a low risk of bias. Trial registration PROSPERO: CRD420250637947.
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institution Kabale University
issn 1477-7819
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publishDate 2025-06-01
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spelling doaj-art-a8e01107c9b5457f9d3e02d29a5d63fe2025-08-20T04:03:03ZengBMCWorld Journal of Surgical Oncology1477-78192025-06-0123111210.1186/s12957-025-03895-yRisk prediction models for permanence of temporary stoma after radical surgery of rectal cancer: a systematic reviewWenjing Tan0Shiyin Cai1Juanqin Wu2Wenke Wu3Shan Wang4Yaqiu Li5Lulu Liu6Liping Tang7Ying Cao8Nursing Department, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityNursing Department, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityNursing Department, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityNursing Department, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityNursing Department, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityNursing Department, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityNursing Department, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityNursing Department, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityNursing Department, The 1st Affiliated Hospital, Jiangxi Medical College, Nanchang UniversityAbstract Objective To methodologically assess the prediction model for temporary stoma permanence in patients with rectal cancer and provide evidence-based guidance for the construction and clinical application of related models. Methods From launch to January 3, 2025, computer searches were performed in nine databases. Two researchers independently searched the literature, and the Critical Appraisal and Data Extraction Checklist for Systematic Evaluation of Predictive Modelling was used to extract data. The Predictive Modelling Research Risk of Bias Assessment Tool was used to assess the studies’ applicability and risk of bias. Results Nine studies were incorporated, exhibiting AUC/C-index values between 0.612 and 0.942, signifying good predictive efficacy in some models. Nonetheless, the included studies showed restricted applicability and a high risk of bias, especially regarding the selection of research populations and data analysis. The predominant determinants across models encompassed T-stage, neoadjuvant chemoradiotherapy, American Society of Anesthesiologists score, carcinoembryonic antigen level, distant metastasis, lymph node metastasis, anastomotic leakage, and age. Conclusion Current prediction models for temporary stoma permanence in rectal cancer patients exhibit significant limitations. In order to improve the accuracy of clinical predictions and inform clinical decision-making, future research should improve study design and reporting standards, as well as build and verify a prediction model that is highly applicable to real-world clinical demands and has a low risk of bias. Trial registration PROSPERO: CRD420250637947.https://doi.org/10.1186/s12957-025-03895-yPermanence of temporary stomaRisk prediction modelSystematic review
spellingShingle Wenjing Tan
Shiyin Cai
Juanqin Wu
Wenke Wu
Shan Wang
Yaqiu Li
Lulu Liu
Liping Tang
Ying Cao
Risk prediction models for permanence of temporary stoma after radical surgery of rectal cancer: a systematic review
World Journal of Surgical Oncology
Permanence of temporary stoma
Risk prediction model
Systematic review
title Risk prediction models for permanence of temporary stoma after radical surgery of rectal cancer: a systematic review
title_full Risk prediction models for permanence of temporary stoma after radical surgery of rectal cancer: a systematic review
title_fullStr Risk prediction models for permanence of temporary stoma after radical surgery of rectal cancer: a systematic review
title_full_unstemmed Risk prediction models for permanence of temporary stoma after radical surgery of rectal cancer: a systematic review
title_short Risk prediction models for permanence of temporary stoma after radical surgery of rectal cancer: a systematic review
title_sort risk prediction models for permanence of temporary stoma after radical surgery of rectal cancer a systematic review
topic Permanence of temporary stoma
Risk prediction model
Systematic review
url https://doi.org/10.1186/s12957-025-03895-y
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