iCLIP predicts the dual splicing effects of TIA-RNA interactions.

iCLIP predicts the dual splicing effects of TIA-RNA interactions.

The regulation of alternative splicing involves interactions between RNA-binding proteins and pre-mRNA positions close to the splice sites. T-cell intracellular antigen 1 (TIA1) and TIA1-like 1 (TIAL1) locally enhance exon inclusion by recruiting U1 snRNP to 5' splice sites. However, effects of...

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Bibliographic Details
Main Authors: Zhen Wang, Melis Kayikci, Michael Briese, Kathi Zarnack, Nicholas M Luscombe, Gregor Rot, Blaž Zupan, Tomaž Curk, Jernej Ule
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS Biology
Online Access:https://journals.plos.org/plosbiology/article/file?id=10.1371/journal.pbio.1000530&type=printable
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