Radiographic Soft Tissue Thickness Is Not a Risk Factor for Infection after Primary Total Ankle Arthroplasty

Category: Ankle; Ankle Arthritis Introduction/Purpose: Total ankle arthroplasty (TAA) is a commonly performed surgical procedure to address end-stage arthritis. Previous studies have suggested that the radiographic soft tissue thickness may be a predictor of complications including periprosthetic jo...

Full description

Saved in:
Bibliographic Details
Main Authors: Albert T. Anastasio MD, Kevin Wu BS, Katherine Kutzer BS, Alexandra Krez MD, James K. DeOrio MD, Mark E. Easley MD, James A. Nunley MD, Samuel B. Adams MD
Format: Article
Language:English
Published: SAGE Publishing 2024-12-01
Series:Foot & Ankle Orthopaedics
Online Access:https://doi.org/10.1177/2473011424S00462
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850240331800379392
author Albert T. Anastasio MD
Kevin Wu BS
Katherine Kutzer BS
Alexandra Krez MD
James K. DeOrio MD
Mark E. Easley MD
James A. Nunley MD
Samuel B. Adams MD
author_facet Albert T. Anastasio MD
Kevin Wu BS
Katherine Kutzer BS
Alexandra Krez MD
James K. DeOrio MD
Mark E. Easley MD
James A. Nunley MD
Samuel B. Adams MD
author_sort Albert T. Anastasio MD
collection DOAJ
description Category: Ankle; Ankle Arthritis Introduction/Purpose: Total ankle arthroplasty (TAA) is a commonly performed surgical procedure to address end-stage arthritis. Previous studies have suggested that the radiographic soft tissue thickness may be a predictor of complications including periprosthetic joint infection (PJI) after orthopedic surgery. However, there has been limited studies exploring the use of radiographic soft tissue thickness in TAA. The purpose of this study was to evaluate the predictive capabilities of radiographic soft-tissue thickness for PJI following TAA. Methods: A retrospective analysis of 323 patients at a single institution who underwent primary TAA from 2003 to 2019 was conducted. Patient characteristics, including age, sex, body mass index (BMI), and comorbidities such as diabetes, smoking status, and etiology of ankle injury were recorded. Preoperative radiographic measurements, including the Tibial-Tissue and Talus-Tissue distances were recorded. Other perioperative information included prosthesis type, tourniquet time, and time to last follow-up. Logistic regression was utilized to examine the relationship between these factors and the occurrence of PJI. Results: Of the 323 patients, there were 6 patients (1.86%) who developed a PJI. The logistic regression analysis revealed that neither Tibial-Tissue (Odds Ratio: 0.975 [0.947 - 1.004]; p = 0.09) nor Talus-Tissue thickness (Odds Ratio: 0.976 [0.940 - 1.012]; p = 0.18) were significant predictors of PJI. Although not statistically significant, the infected cohort had smaller average Tibial-Tissue (2.20 vs. 2.53 cm; p=0.05) and Talus-Tissue thickness (2.19 vs. 2.44 cm; p=0.36) compared to the non-infected cohort. Conclusion: Despite an association between radiographic soft tissue thickness and infection in other orthopedic surgeries, measurements such as Tibial-Tissue length and Talus-Tissue length were not significant predictors of PJI following primary TAA. These findings underscore the necessity for additional research to identify modifiable risk factors aimed at reducing PJI rates and enhancing patient outcomes.
format Article
id doaj-art-a8cb89f66d09450084cdae792b51db0c
institution OA Journals
issn 2473-0114
language English
publishDate 2024-12-01
publisher SAGE Publishing
record_format Article
series Foot & Ankle Orthopaedics
spelling doaj-art-a8cb89f66d09450084cdae792b51db0c2025-08-20T02:00:54ZengSAGE PublishingFoot & Ankle Orthopaedics2473-01142024-12-01910.1177/2473011424S00462Radiographic Soft Tissue Thickness Is Not a Risk Factor for Infection after Primary Total Ankle ArthroplastyAlbert T. Anastasio MDKevin Wu BSKatherine Kutzer BSAlexandra Krez MDJames K. DeOrio MDMark E. Easley MDJames A. Nunley MDSamuel B. Adams MDCategory: Ankle; Ankle Arthritis Introduction/Purpose: Total ankle arthroplasty (TAA) is a commonly performed surgical procedure to address end-stage arthritis. Previous studies have suggested that the radiographic soft tissue thickness may be a predictor of complications including periprosthetic joint infection (PJI) after orthopedic surgery. However, there has been limited studies exploring the use of radiographic soft tissue thickness in TAA. The purpose of this study was to evaluate the predictive capabilities of radiographic soft-tissue thickness for PJI following TAA. Methods: A retrospective analysis of 323 patients at a single institution who underwent primary TAA from 2003 to 2019 was conducted. Patient characteristics, including age, sex, body mass index (BMI), and comorbidities such as diabetes, smoking status, and etiology of ankle injury were recorded. Preoperative radiographic measurements, including the Tibial-Tissue and Talus-Tissue distances were recorded. Other perioperative information included prosthesis type, tourniquet time, and time to last follow-up. Logistic regression was utilized to examine the relationship between these factors and the occurrence of PJI. Results: Of the 323 patients, there were 6 patients (1.86%) who developed a PJI. The logistic regression analysis revealed that neither Tibial-Tissue (Odds Ratio: 0.975 [0.947 - 1.004]; p = 0.09) nor Talus-Tissue thickness (Odds Ratio: 0.976 [0.940 - 1.012]; p = 0.18) were significant predictors of PJI. Although not statistically significant, the infected cohort had smaller average Tibial-Tissue (2.20 vs. 2.53 cm; p=0.05) and Talus-Tissue thickness (2.19 vs. 2.44 cm; p=0.36) compared to the non-infected cohort. Conclusion: Despite an association between radiographic soft tissue thickness and infection in other orthopedic surgeries, measurements such as Tibial-Tissue length and Talus-Tissue length were not significant predictors of PJI following primary TAA. These findings underscore the necessity for additional research to identify modifiable risk factors aimed at reducing PJI rates and enhancing patient outcomes.https://doi.org/10.1177/2473011424S00462
spellingShingle Albert T. Anastasio MD
Kevin Wu BS
Katherine Kutzer BS
Alexandra Krez MD
James K. DeOrio MD
Mark E. Easley MD
James A. Nunley MD
Samuel B. Adams MD
Radiographic Soft Tissue Thickness Is Not a Risk Factor for Infection after Primary Total Ankle Arthroplasty
Foot & Ankle Orthopaedics
title Radiographic Soft Tissue Thickness Is Not a Risk Factor for Infection after Primary Total Ankle Arthroplasty
title_full Radiographic Soft Tissue Thickness Is Not a Risk Factor for Infection after Primary Total Ankle Arthroplasty
title_fullStr Radiographic Soft Tissue Thickness Is Not a Risk Factor for Infection after Primary Total Ankle Arthroplasty
title_full_unstemmed Radiographic Soft Tissue Thickness Is Not a Risk Factor for Infection after Primary Total Ankle Arthroplasty
title_short Radiographic Soft Tissue Thickness Is Not a Risk Factor for Infection after Primary Total Ankle Arthroplasty
title_sort radiographic soft tissue thickness is not a risk factor for infection after primary total ankle arthroplasty
url https://doi.org/10.1177/2473011424S00462
work_keys_str_mv AT alberttanastasiomd radiographicsofttissuethicknessisnotariskfactorforinfectionafterprimarytotalanklearthroplasty
AT kevinwubs radiographicsofttissuethicknessisnotariskfactorforinfectionafterprimarytotalanklearthroplasty
AT katherinekutzerbs radiographicsofttissuethicknessisnotariskfactorforinfectionafterprimarytotalanklearthroplasty
AT alexandrakrezmd radiographicsofttissuethicknessisnotariskfactorforinfectionafterprimarytotalanklearthroplasty
AT jameskdeoriomd radiographicsofttissuethicknessisnotariskfactorforinfectionafterprimarytotalanklearthroplasty
AT markeeasleymd radiographicsofttissuethicknessisnotariskfactorforinfectionafterprimarytotalanklearthroplasty
AT jamesanunleymd radiographicsofttissuethicknessisnotariskfactorforinfectionafterprimarytotalanklearthroplasty
AT samuelbadamsmd radiographicsofttissuethicknessisnotariskfactorforinfectionafterprimarytotalanklearthroplasty