Developmental Defects in Trisomy 21 and Mouse Models

Aneuploidies have diverse phenotypic consequences, ranging from mental retardation and developmental abnormalities to susceptibility to common phenotypes and various neoplasms. This review focuses on the developmental defects of murine models of a prototype human aneuploidy: trisomy 21 (Down syndrom...

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Bibliographic Details
Main Authors: Jean Maurice Delabar, Revital Aflalo-Rattenbac, Nicole Créau
Format: Article
Language:English
Published: Wiley 2006-01-01
Series:The Scientific World Journal
Online Access:http://dx.doi.org/10.1100/tsw.2006.322
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