Single-cell ligand–receptor profiling reveals an immunotherapy-responsive subtype and prognostic signature in triple-negative breast cancer

Single-cell ligand–receptor profiling reveals an immunotherapy-responsive subtype and prognostic signature in triple-negative breast cancer

BackgroundTriple-negative breast cancer (TNBC) is an aggressive form of cancer that lacks specific targeted therapies. Although ligand–receptor (LR) interactions play a crucial role in intercellular communication and contribute to tumor heterogeneity, their molecular details and potential as prognos...

Full description

Saved in:
Bibliographic Details
Main Authors: Chuanzhi Chen, Jiahui Qi, Weichao Lin, Chunlan Fu, Xin Jin
Format: Article
Language:English
Published: Frontiers Media S.A. 2025-06-01
Series:Frontiers in Immunology
Subjects:
tumor microenvironment
ligand-receptor interactions
triple-negative breast cancer
prognostic model
immunotherapy
immune checkpoints
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2025.1590951/full
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items

Similar Items