The Role of LC-MS in Profiling Bioactive Compounds from Plant Waste for Cosmetic Applications: A General Overview
The agro-industrial sector produces large amounts of by-products that have a high environmental impact, so it has become essential to recover food waste at all levels. This is because it often contains bioactive molecules that can be a valuable source of new products such as animal feed, biopolymers...
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MDPI AG
2025-07-01
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| Series: | Plants |
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| Online Access: | https://www.mdpi.com/2223-7747/14/15/2284 |
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| author | Gilda D’Urso Alessandra Capuano Francesca Fantasma Maria Giovanna Chini Vincenzo De Felice Gabriella Saviano Gianluigi Lauro Agostino Casapullo Giuseppe Bifulco Maria Iorizzi |
| author_facet | Gilda D’Urso Alessandra Capuano Francesca Fantasma Maria Giovanna Chini Vincenzo De Felice Gabriella Saviano Gianluigi Lauro Agostino Casapullo Giuseppe Bifulco Maria Iorizzi |
| author_sort | Gilda D’Urso |
| collection | DOAJ |
| description | The agro-industrial sector produces large amounts of by-products that have a high environmental impact, so it has become essential to recover food waste at all levels. This is because it often contains bioactive molecules that can be a valuable source of new products such as animal feed, biopolymers, or products for human use, (e.g., cosmetics and nutraceuticals) due to its antioxidant, antimicrobial, and anti-inflammatory properties. Advanced analytical methodologies such as liquid chromatography coupled to mass spectrometry (LC-MS) are crucial for the characterisation of bioactive chemicals in these waste materials. LC-MS enables both targeted and untargeted metabolomic approaches, facilitating the identification and quantification of a wide range of secondary metabolites, including polyphenols, flavonoids, alkaloids, and terpenoids. The choice of extraction methodology is essential for the precise identification and quantification of these metabolites. This study provides an overview of LC-MS as an effective tool for analysing complex extracts derived from plant waste, discussing both methodological aspects and typical bioactive metabolites identified, and offering examples of their potential applications in cosmeceutics. |
| format | Article |
| id | doaj-art-a88e3d5a3e3a4eaebb4711b635a6ddb9 |
| institution | DOAJ |
| issn | 2223-7747 |
| language | English |
| publishDate | 2025-07-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Plants |
| spelling | doaj-art-a88e3d5a3e3a4eaebb4711b635a6ddb92025-08-20T03:02:58ZengMDPI AGPlants2223-77472025-07-011415228410.3390/plants14152284The Role of LC-MS in Profiling Bioactive Compounds from Plant Waste for Cosmetic Applications: A General OverviewGilda D’Urso0Alessandra Capuano1Francesca Fantasma2Maria Giovanna Chini3Vincenzo De Felice4Gabriella Saviano5Gianluigi Lauro6Agostino Casapullo7Giuseppe Bifulco8Maria Iorizzi9Department of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Salerno, ItalyDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Salerno, ItalyDepartment of Biosciences and Territory, University of Molise, Contrada Fonte Lappone, 86090 Pesche, Isernia, ItalyDepartment of Biosciences and Territory, University of Molise, Contrada Fonte Lappone, 86090 Pesche, Isernia, ItalyDepartment of Biosciences and Territory, University of Molise, Contrada Fonte Lappone, 86090 Pesche, Isernia, ItalyDepartment of Biosciences and Territory, University of Molise, Contrada Fonte Lappone, 86090 Pesche, Isernia, ItalyDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Salerno, ItalyDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Salerno, ItalyDepartment of Pharmacy, University of Salerno, Via Giovanni Paolo II 132, 84084 Fisciano, Salerno, ItalyDepartment of Biosciences and Territory, University of Molise, Contrada Fonte Lappone, 86090 Pesche, Isernia, ItalyThe agro-industrial sector produces large amounts of by-products that have a high environmental impact, so it has become essential to recover food waste at all levels. This is because it often contains bioactive molecules that can be a valuable source of new products such as animal feed, biopolymers, or products for human use, (e.g., cosmetics and nutraceuticals) due to its antioxidant, antimicrobial, and anti-inflammatory properties. Advanced analytical methodologies such as liquid chromatography coupled to mass spectrometry (LC-MS) are crucial for the characterisation of bioactive chemicals in these waste materials. LC-MS enables both targeted and untargeted metabolomic approaches, facilitating the identification and quantification of a wide range of secondary metabolites, including polyphenols, flavonoids, alkaloids, and terpenoids. The choice of extraction methodology is essential for the precise identification and quantification of these metabolites. This study provides an overview of LC-MS as an effective tool for analysing complex extracts derived from plant waste, discussing both methodological aspects and typical bioactive metabolites identified, and offering examples of their potential applications in cosmeceutics.https://www.mdpi.com/2223-7747/14/15/2284plant wasteLC-MS analysismetabolomicscosmetic applicationsbioactive compounds |
| spellingShingle | Gilda D’Urso Alessandra Capuano Francesca Fantasma Maria Giovanna Chini Vincenzo De Felice Gabriella Saviano Gianluigi Lauro Agostino Casapullo Giuseppe Bifulco Maria Iorizzi The Role of LC-MS in Profiling Bioactive Compounds from Plant Waste for Cosmetic Applications: A General Overview Plants plant waste LC-MS analysis metabolomics cosmetic applications bioactive compounds |
| title | The Role of LC-MS in Profiling Bioactive Compounds from Plant Waste for Cosmetic Applications: A General Overview |
| title_full | The Role of LC-MS in Profiling Bioactive Compounds from Plant Waste for Cosmetic Applications: A General Overview |
| title_fullStr | The Role of LC-MS in Profiling Bioactive Compounds from Plant Waste for Cosmetic Applications: A General Overview |
| title_full_unstemmed | The Role of LC-MS in Profiling Bioactive Compounds from Plant Waste for Cosmetic Applications: A General Overview |
| title_short | The Role of LC-MS in Profiling Bioactive Compounds from Plant Waste for Cosmetic Applications: A General Overview |
| title_sort | role of lc ms in profiling bioactive compounds from plant waste for cosmetic applications a general overview |
| topic | plant waste LC-MS analysis metabolomics cosmetic applications bioactive compounds |
| url | https://www.mdpi.com/2223-7747/14/15/2284 |
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