A Case of Chorioretinitis with Retinal Angiomatous Proliferation
A 48-year-old woman had an acute blurred vision in the right eye immediately after drainage of liver abscess. Her best corrected visual acuity (BCVA) was 8/400; fundus photography suggested the diagnosis of endogenous endophthalmitis with chorioretinitis and vitritis. Due to the bad systemic conditi...
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Wiley
2021-01-01
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| Series: | Case Reports in Ophthalmological Medicine |
| Online Access: | http://dx.doi.org/10.1155/2021/3564939 |
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| author | Yanru Chen Mingyan Wei Qian Chen Minghan Li |
| author_facet | Yanru Chen Mingyan Wei Qian Chen Minghan Li |
| author_sort | Yanru Chen |
| collection | DOAJ |
| description | A 48-year-old woman had an acute blurred vision in the right eye immediately after drainage of liver abscess. Her best corrected visual acuity (BCVA) was 8/400; fundus photography suggested the diagnosis of endogenous endophthalmitis with chorioretinitis and vitritis. Due to the bad systemic condition, a systemic antibiotic combined with periocular triamcinolone (TA) was carried out first. Inflammatory cells in the vitreous cavity were decreased after treatment; however, fundus fluorescein angiography (FFA) showed abnormal dilation and leakage of the capillaries and retinal-choroidal anastomose, supporting that there was retinal angiomatous proliferation (RAP). Vitreous interleukin-6 (IL-6) was only slightly elevated; the ratio of interleukin-10 (IL-10) and IL-6 was less than 1, and the etiological test was negative. After receiving intravitreal vancomycin injection combined with periocular TA injection, the patient’s BCVA was improved from 16/400 to 20/400 with a reduction in vitreous inflammatory cells. However, the patient’s RAP was progressed and her BCVA was dramatically decreased to count finger/30 cm. After intravitreal injection of ranibizumab, the patient’s BCVA was 5/400 with a significant shrink in lesions and absorption of hemorrhage, exudation, and fluid. Thus, we suggest that early anti-inflammatory treatment in conjunction with anti-VEGF may achieve a better prognosis in patients with inflammatory retinal angiomatous proliferation (RAP). |
| format | Article |
| id | doaj-art-a86e50f616d34923af5b183c5c56e5d2 |
| institution | Kabale University |
| issn | 2090-6730 |
| language | English |
| publishDate | 2021-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Ophthalmological Medicine |
| spelling | doaj-art-a86e50f616d34923af5b183c5c56e5d22025-02-03T05:59:58ZengWileyCase Reports in Ophthalmological Medicine2090-67302021-01-01202110.1155/2021/3564939A Case of Chorioretinitis with Retinal Angiomatous ProliferationYanru Chen0Mingyan Wei1Qian Chen2Minghan Li3Xiamen University Affiliated Xiamen Eye CenterDepartment of OphthalmologyDepartment of OphthalmologyXiamen University Affiliated Xiamen Eye CenterA 48-year-old woman had an acute blurred vision in the right eye immediately after drainage of liver abscess. Her best corrected visual acuity (BCVA) was 8/400; fundus photography suggested the diagnosis of endogenous endophthalmitis with chorioretinitis and vitritis. Due to the bad systemic condition, a systemic antibiotic combined with periocular triamcinolone (TA) was carried out first. Inflammatory cells in the vitreous cavity were decreased after treatment; however, fundus fluorescein angiography (FFA) showed abnormal dilation and leakage of the capillaries and retinal-choroidal anastomose, supporting that there was retinal angiomatous proliferation (RAP). Vitreous interleukin-6 (IL-6) was only slightly elevated; the ratio of interleukin-10 (IL-10) and IL-6 was less than 1, and the etiological test was negative. After receiving intravitreal vancomycin injection combined with periocular TA injection, the patient’s BCVA was improved from 16/400 to 20/400 with a reduction in vitreous inflammatory cells. However, the patient’s RAP was progressed and her BCVA was dramatically decreased to count finger/30 cm. After intravitreal injection of ranibizumab, the patient’s BCVA was 5/400 with a significant shrink in lesions and absorption of hemorrhage, exudation, and fluid. Thus, we suggest that early anti-inflammatory treatment in conjunction with anti-VEGF may achieve a better prognosis in patients with inflammatory retinal angiomatous proliferation (RAP).http://dx.doi.org/10.1155/2021/3564939 |
| spellingShingle | Yanru Chen Mingyan Wei Qian Chen Minghan Li A Case of Chorioretinitis with Retinal Angiomatous Proliferation Case Reports in Ophthalmological Medicine |
| title | A Case of Chorioretinitis with Retinal Angiomatous Proliferation |
| title_full | A Case of Chorioretinitis with Retinal Angiomatous Proliferation |
| title_fullStr | A Case of Chorioretinitis with Retinal Angiomatous Proliferation |
| title_full_unstemmed | A Case of Chorioretinitis with Retinal Angiomatous Proliferation |
| title_short | A Case of Chorioretinitis with Retinal Angiomatous Proliferation |
| title_sort | case of chorioretinitis with retinal angiomatous proliferation |
| url | http://dx.doi.org/10.1155/2021/3564939 |
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