The efficacy and mechanisms of low-intensity transcranial ultrasound stimulation on pain: a systematic review of human and animal studies

The efficacy and mechanisms of low-intensity transcranial ultrasound stimulation on pain: a systematic review of human and animal studies

Abstract Background Low-intensity transcranial ultrasound stimulation (LITUS) is an emerging non-invasive neuromodulation technique for pain treatment, with the unique ability to modulate deep brain nuclei associated with pain. The aim of this study is to systematically review and summarize the evid...

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Bibliographic Details
Main Authors: Hao-Ran Xu, Yiu-Liang Yi, Chuan Xue, Zi-Qi Guo, Li Ding, Jie Jia
Format: Article
Language:English
Published: BMC 2025-07-01
Series:The Journal of Headache and Pain
Subjects:
Transcranial ultrasound
Low-intensity transcranial ultrasound
Pain
Neuromodulation
Effectiveness
Online Access:https://doi.org/10.1186/s10194-025-02096-y
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