Upregulation of PD-1 Expression and High sPD-L1 Levels Associated with COVID-19 Severity

Upregulation of PD-1 Expression and High sPD-L1 Levels Associated with COVID-19 Severity

COVID-19 has several mechanisms that can lead to lymphocyte depletion/exhaustion. The checkpoint inhibitor molecule programmed death protein 1 (PD-1) and its programmed death-ligand 1 (PDL-1) play an important role in inhibiting cellular activity as well as the depletion of these cells. In this stud...

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Main Authors: Danielle Rosa Beserra, Ricardo Wesley Alberca, Anna Claudia Calvielli Castelo Branco, Luana de Mendonça Oliveira, Milena Mary de Souza Andrade, Sarah Cristina Gozzi-Silva, Franciane Mouradian Emidio Teixeira, Tatiana Mina Yendo, Alberto José da Silva Duarte, Maria Notomi Sato
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Immunology Research
Online Access:http://dx.doi.org/10.1155/2022/9764002
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