Colorectal Cancer Arising in a Colon Interposition After Esophageal Reconstruction: The Medical Oncology Perspective

Severe esophageal disease can be remedied with colonic interposition, a surgical procedure in which the resected esophagus is replaced by a segment of colon. The development of adenocarcinoma in the colon conduit is a rare but growing long-term complication of this procedure. Here, we present a case...

Full description

Saved in:
Bibliographic Details
Main Authors: Nikita V. Baclig, Aileen T. MacAndrew, Jane Yanagawa, Alireza Sedarat, Bernard J. Katz, David W. Dawson, Mark D. Girgis, Lee S. Rosen
Format: Article
Language:English
Published: American College of Physicians 2025-03-01
Series:Annals of Internal Medicine: Clinical Cases
Online Access:https://www.acpjournals.org/doi/10.7326/aimcc.2024.0751
Tags: Add Tag
No Tags, Be the first to tag this record!
_version_ 1850182804670775296
author Nikita V. Baclig
Aileen T. MacAndrew
Jane Yanagawa
Alireza Sedarat
Bernard J. Katz
David W. Dawson
Mark D. Girgis
Lee S. Rosen
author_facet Nikita V. Baclig
Aileen T. MacAndrew
Jane Yanagawa
Alireza Sedarat
Bernard J. Katz
David W. Dawson
Mark D. Girgis
Lee S. Rosen
author_sort Nikita V. Baclig
collection DOAJ
description Severe esophageal disease can be remedied with colonic interposition, a surgical procedure in which the resected esophagus is replaced by a segment of colon. The development of adenocarcinoma in the colon conduit is a rare but growing long-term complication of this procedure. Here, we present a case of colorectal cancer that developed decades after colonic interposition for childhood esophageal injury due to caustic ingestion. We highlight the challenges inherent in evaluation, treatment, surveillance, and survivorship for this unfortunate complication and describe our institution's successful approach to this complex case.
format Article
id doaj-art-a8395d4de8bb4877b2cc0c00a4b8cde8
institution OA Journals
issn 2767-7664
language English
publishDate 2025-03-01
publisher American College of Physicians
record_format Article
series Annals of Internal Medicine: Clinical Cases
spelling doaj-art-a8395d4de8bb4877b2cc0c00a4b8cde82025-08-20T02:17:33ZengAmerican College of PhysiciansAnnals of Internal Medicine: Clinical Cases2767-76642025-03-014310.7326/aimcc.2024.0751Colorectal Cancer Arising in a Colon Interposition After Esophageal Reconstruction: The Medical Oncology PerspectiveNikita V. Baclig0Aileen T. MacAndrew1Jane Yanagawa2Alireza Sedarat3Bernard J. Katz4David W. Dawson5Mark D. Girgis6Lee S. Rosen71Division of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California1Division of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California3Department of Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California4Division of Digestive Diseases, Department of Medicine, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California5Department of Family Medicine, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California6Jonsson Comprehensive Cancer Center and Department of Pathology and Laboratory Medicine, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California3Department of Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, California1Division of Hematology and Oncology, Department of Medicine, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CaliforniaSevere esophageal disease can be remedied with colonic interposition, a surgical procedure in which the resected esophagus is replaced by a segment of colon. The development of adenocarcinoma in the colon conduit is a rare but growing long-term complication of this procedure. Here, we present a case of colorectal cancer that developed decades after colonic interposition for childhood esophageal injury due to caustic ingestion. We highlight the challenges inherent in evaluation, treatment, surveillance, and survivorship for this unfortunate complication and describe our institution's successful approach to this complex case.https://www.acpjournals.org/doi/10.7326/aimcc.2024.0751
spellingShingle Nikita V. Baclig
Aileen T. MacAndrew
Jane Yanagawa
Alireza Sedarat
Bernard J. Katz
David W. Dawson
Mark D. Girgis
Lee S. Rosen
Colorectal Cancer Arising in a Colon Interposition After Esophageal Reconstruction: The Medical Oncology Perspective
Annals of Internal Medicine: Clinical Cases
title Colorectal Cancer Arising in a Colon Interposition After Esophageal Reconstruction: The Medical Oncology Perspective
title_full Colorectal Cancer Arising in a Colon Interposition After Esophageal Reconstruction: The Medical Oncology Perspective
title_fullStr Colorectal Cancer Arising in a Colon Interposition After Esophageal Reconstruction: The Medical Oncology Perspective
title_full_unstemmed Colorectal Cancer Arising in a Colon Interposition After Esophageal Reconstruction: The Medical Oncology Perspective
title_short Colorectal Cancer Arising in a Colon Interposition After Esophageal Reconstruction: The Medical Oncology Perspective
title_sort colorectal cancer arising in a colon interposition after esophageal reconstruction the medical oncology perspective
url https://www.acpjournals.org/doi/10.7326/aimcc.2024.0751
work_keys_str_mv AT nikitavbaclig colorectalcancerarisinginacoloninterpositionafteresophagealreconstructionthemedicaloncologyperspective
AT aileentmacandrew colorectalcancerarisinginacoloninterpositionafteresophagealreconstructionthemedicaloncologyperspective
AT janeyanagawa colorectalcancerarisinginacoloninterpositionafteresophagealreconstructionthemedicaloncologyperspective
AT alirezasedarat colorectalcancerarisinginacoloninterpositionafteresophagealreconstructionthemedicaloncologyperspective
AT bernardjkatz colorectalcancerarisinginacoloninterpositionafteresophagealreconstructionthemedicaloncologyperspective
AT davidwdawson colorectalcancerarisinginacoloninterpositionafteresophagealreconstructionthemedicaloncologyperspective
AT markdgirgis colorectalcancerarisinginacoloninterpositionafteresophagealreconstructionthemedicaloncologyperspective
AT leesrosen colorectalcancerarisinginacoloninterpositionafteresophagealreconstructionthemedicaloncologyperspective