All About Prostaglandin Analogues in Eye

Glaucoma is a leading cause of impairment of vision worldwide. Raised intraocular pressure can cause damage to both optic nerve and retinal ganglion cells. Reducing intraocular pressure is the only modifiable risk factor for this disease available presently. It can be achieved either by surgical or...

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Main Authors: Priti Kumari, Madhu Bhoot
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2020-01-01
Series:Delhi Journal of Ophthalmology
Subjects:
Online Access:https://journals.lww.com/10.7869/djo.518
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author Priti Kumari
Madhu Bhoot
author_facet Priti Kumari
Madhu Bhoot
author_sort Priti Kumari
collection DOAJ
description Glaucoma is a leading cause of impairment of vision worldwide. Raised intraocular pressure can cause damage to both optic nerve and retinal ganglion cells. Reducing intraocular pressure is the only modifiable risk factor for this disease available presently. It can be achieved either by surgical or medical treatment. Pharmacotherapy is the mainstay of treatment for glaucoma patients. Prostaglandins analogues have replaced beta blockers as the first line anti-glaucoma drug. Their single dose per day, better diurnal control of IOP and long washout period has ensured better compliance and better results in various forms of glaucoma. A lot of clinical research is ongoing in developing new prostaglandin derivatives with safer profiles and more targeted action. This article will be reviewing the various merits and demerits of prostaglandin analogues in practice as well as shed some light on the newer drugs in pipeline.
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institution Kabale University
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2454-2784
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publishDate 2020-01-01
publisher Wolters Kluwer Medknow Publications
record_format Article
series Delhi Journal of Ophthalmology
spelling doaj-art-a82c5988008146b8afd58a133d5e479f2025-08-20T03:52:29ZengWolters Kluwer Medknow PublicationsDelhi Journal of Ophthalmology0972-02002454-27842020-01-0130371010.7869/djo.518All About Prostaglandin Analogues in EyePriti KumariMadhu BhootGlaucoma is a leading cause of impairment of vision worldwide. Raised intraocular pressure can cause damage to both optic nerve and retinal ganglion cells. Reducing intraocular pressure is the only modifiable risk factor for this disease available presently. It can be achieved either by surgical or medical treatment. Pharmacotherapy is the mainstay of treatment for glaucoma patients. Prostaglandins analogues have replaced beta blockers as the first line anti-glaucoma drug. Their single dose per day, better diurnal control of IOP and long washout period has ensured better compliance and better results in various forms of glaucoma. A lot of clinical research is ongoing in developing new prostaglandin derivatives with safer profiles and more targeted action. This article will be reviewing the various merits and demerits of prostaglandin analogues in practice as well as shed some light on the newer drugs in pipeline.https://journals.lww.com/10.7869/djo.518glaucomaprostaglandinsanti-glaucoma drugs
spellingShingle Priti Kumari
Madhu Bhoot
All About Prostaglandin Analogues in Eye
Delhi Journal of Ophthalmology
glaucoma
prostaglandins
anti-glaucoma drugs
title All About Prostaglandin Analogues in Eye
title_full All About Prostaglandin Analogues in Eye
title_fullStr All About Prostaglandin Analogues in Eye
title_full_unstemmed All About Prostaglandin Analogues in Eye
title_short All About Prostaglandin Analogues in Eye
title_sort all about prostaglandin analogues in eye
topic glaucoma
prostaglandins
anti-glaucoma drugs
url https://journals.lww.com/10.7869/djo.518
work_keys_str_mv AT pritikumari allaboutprostaglandinanaloguesineye
AT madhubhoot allaboutprostaglandinanaloguesineye