Relationship between Prolactin, Chronic Kidney Disease, and Cardiovascular Risk
CKD has a high prevalence worldwide, mainly due to its main etiologies—diabetes and hypertension. It has high cardiovascular morbidity and mortality, with traditional risk factors such as atherosclerosis, hypertension, diabetes, smoking, and left ventricular hypertrophy being common. Nontraditional...
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| Format: | Article |
| Language: | English |
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Wiley
2020-01-01
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| Series: | International Journal of Endocrinology |
| Online Access: | http://dx.doi.org/10.1155/2020/9524839 |
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| _version_ | 1832550368624508928 |
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| author | Marclébio Dourado Frederico Cavalcanti Lucio Vilar Amaury Cantilino |
| author_facet | Marclébio Dourado Frederico Cavalcanti Lucio Vilar Amaury Cantilino |
| author_sort | Marclébio Dourado |
| collection | DOAJ |
| description | CKD has a high prevalence worldwide, mainly due to its main etiologies—diabetes and hypertension. It has high cardiovascular morbidity and mortality, with traditional risk factors such as atherosclerosis, hypertension, diabetes, smoking, and left ventricular hypertrophy being common. Nontraditional cardiovascular risk factors, such as anemia, hyperparathyroidism, chronic inflammation, and microalbuminuria, are also well studied. Prolactin is a hormone not only related to lactation but also being considered a uremic toxin by some authors. It accumulates with loss of renal function, and it is associated with cardiovascular outcomes in both normal renal function population and CKD population. The purpose of this narrative review is to raise the main common aspects of CKD, prolactinemia, and cardiovascular risk. |
| format | Article |
| id | doaj-art-a8271796bbfa466f9fe005c201bd2dbc |
| institution | Kabale University |
| issn | 1687-8337 1687-8345 |
| language | English |
| publishDate | 2020-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | International Journal of Endocrinology |
| spelling | doaj-art-a8271796bbfa466f9fe005c201bd2dbc2025-02-03T06:06:54ZengWileyInternational Journal of Endocrinology1687-83371687-83452020-01-01202010.1155/2020/95248399524839Relationship between Prolactin, Chronic Kidney Disease, and Cardiovascular RiskMarclébio Dourado0Frederico Cavalcanti1Lucio Vilar2Amaury Cantilino3Nephrology Department, Medical Sciences Center (CCM), Federal University of Pernambuco, Recife, BrazilNephrology Department, Medical Sciences Center (CCM), Federal University of Pernambuco, Recife, BrazilPostgraduate Program in Neuropsychiatry and Behavioral Sciences, Federal University of Pernambuco, Recife, Pernambuco, BrazilPostgraduate Program in Neuropsychiatry and Behavioral Sciences, Federal University of Pernambuco, Recife, Pernambuco, BrazilCKD has a high prevalence worldwide, mainly due to its main etiologies—diabetes and hypertension. It has high cardiovascular morbidity and mortality, with traditional risk factors such as atherosclerosis, hypertension, diabetes, smoking, and left ventricular hypertrophy being common. Nontraditional cardiovascular risk factors, such as anemia, hyperparathyroidism, chronic inflammation, and microalbuminuria, are also well studied. Prolactin is a hormone not only related to lactation but also being considered a uremic toxin by some authors. It accumulates with loss of renal function, and it is associated with cardiovascular outcomes in both normal renal function population and CKD population. The purpose of this narrative review is to raise the main common aspects of CKD, prolactinemia, and cardiovascular risk.http://dx.doi.org/10.1155/2020/9524839 |
| spellingShingle | Marclébio Dourado Frederico Cavalcanti Lucio Vilar Amaury Cantilino Relationship between Prolactin, Chronic Kidney Disease, and Cardiovascular Risk International Journal of Endocrinology |
| title | Relationship between Prolactin, Chronic Kidney Disease, and Cardiovascular Risk |
| title_full | Relationship between Prolactin, Chronic Kidney Disease, and Cardiovascular Risk |
| title_fullStr | Relationship between Prolactin, Chronic Kidney Disease, and Cardiovascular Risk |
| title_full_unstemmed | Relationship between Prolactin, Chronic Kidney Disease, and Cardiovascular Risk |
| title_short | Relationship between Prolactin, Chronic Kidney Disease, and Cardiovascular Risk |
| title_sort | relationship between prolactin chronic kidney disease and cardiovascular risk |
| url | http://dx.doi.org/10.1155/2020/9524839 |
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