Laser Welding of Micro-Wire Stent Electrode as a Minimally Invasive Endovascular Neural Interface

Minimally invasive endovascular stent electrodes are an emerging technology in neural engineering, designed to minimize the damage to neural tissue. However, conventional stent electrodes often rely on resistive welding and are relatively bulky, restricting their use primarily to large animals or th...

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Main Authors: Bo Wen, Liang Shen, Xiaoyang Kang
Format: Article
Language:English
Published: MDPI AG 2024-12-01
Series:Micromachines
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Online Access:https://www.mdpi.com/2072-666X/16/1/21
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author Bo Wen
Liang Shen
Xiaoyang Kang
author_facet Bo Wen
Liang Shen
Xiaoyang Kang
author_sort Bo Wen
collection DOAJ
description Minimally invasive endovascular stent electrodes are an emerging technology in neural engineering, designed to minimize the damage to neural tissue. However, conventional stent electrodes often rely on resistive welding and are relatively bulky, restricting their use primarily to large animals or thick blood vessels. In this study, the feasibility is explored of fabricating a laser welding stent electrode as small as 300 μm. A high-precision laser welding technique was developed to join micro-wire electrodes without compromising structural integrity or performance. To ensure consistent results, a novel micro-wire welding with platinum pad method was introduced during the welding process. The fabricated electrodes were integrated with stent structures and subjected to detailed electrochemical performance testing to evaluate their potential as neural interface components. The laser-welded endovascular stent electrodes exhibited excellent electrochemical properties, including low impedance and stable charge transfer capabilities. At the same time, in this study, a simulation is conducted of the electrode distribution and arrangement on the stent structure, optimizing the utilization of the available surface area for enhanced functionality. These results demonstrate the potential of the fabricated electrodes for high-performance neural interfacing in endovascular applications. The approach provided a promising solution for advancing endovascular neural engineering technologies, particularly in applications requiring compact electrode designs.
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spelling doaj-art-a826b73dbef24ef79a70d04d878ac5282025-01-24T13:41:52ZengMDPI AGMicromachines2072-666X2024-12-011612110.3390/mi16010021Laser Welding of Micro-Wire Stent Electrode as a Minimally Invasive Endovascular Neural InterfaceBo Wen0Liang Shen1Xiaoyang Kang2Laboratory for Neural Interface and Brain Computer Interface, Engineering Research Center of AI & Robotics, Ministry of Education, Shanghai Engineering Research Center of AI & Robotics, MOE Frontiers Center for Brain Science, State Key Laboratory of Medical Neurobiology, Institute of AI & Robotics, Academy for Engineering & Technology, Fudan University, Shanghai 200433, ChinaLaboratory for Neural Interface and Brain Computer Interface, Engineering Research Center of AI & Robotics, Ministry of Education, Shanghai Engineering Research Center of AI & Robotics, MOE Frontiers Center for Brain Science, State Key Laboratory of Medical Neurobiology, Institute of AI & Robotics, Academy for Engineering & Technology, Fudan University, Shanghai 200433, ChinaLaboratory for Neural Interface and Brain Computer Interface, Engineering Research Center of AI & Robotics, Ministry of Education, Shanghai Engineering Research Center of AI & Robotics, MOE Frontiers Center for Brain Science, State Key Laboratory of Medical Neurobiology, Institute of AI & Robotics, Academy for Engineering & Technology, Fudan University, Shanghai 200433, ChinaMinimally invasive endovascular stent electrodes are an emerging technology in neural engineering, designed to minimize the damage to neural tissue. However, conventional stent electrodes often rely on resistive welding and are relatively bulky, restricting their use primarily to large animals or thick blood vessels. In this study, the feasibility is explored of fabricating a laser welding stent electrode as small as 300 μm. A high-precision laser welding technique was developed to join micro-wire electrodes without compromising structural integrity or performance. To ensure consistent results, a novel micro-wire welding with platinum pad method was introduced during the welding process. The fabricated electrodes were integrated with stent structures and subjected to detailed electrochemical performance testing to evaluate their potential as neural interface components. The laser-welded endovascular stent electrodes exhibited excellent electrochemical properties, including low impedance and stable charge transfer capabilities. At the same time, in this study, a simulation is conducted of the electrode distribution and arrangement on the stent structure, optimizing the utilization of the available surface area for enhanced functionality. These results demonstrate the potential of the fabricated electrodes for high-performance neural interfacing in endovascular applications. The approach provided a promising solution for advancing endovascular neural engineering technologies, particularly in applications requiring compact electrode designs.https://www.mdpi.com/2072-666X/16/1/21endovascular stent electrodelaser weldingelectrochemical impedance spectroscopy (EIS)minimally invasive brain–computer interface
spellingShingle Bo Wen
Liang Shen
Xiaoyang Kang
Laser Welding of Micro-Wire Stent Electrode as a Minimally Invasive Endovascular Neural Interface
Micromachines
endovascular stent electrode
laser welding
electrochemical impedance spectroscopy (EIS)
minimally invasive brain–computer interface
title Laser Welding of Micro-Wire Stent Electrode as a Minimally Invasive Endovascular Neural Interface
title_full Laser Welding of Micro-Wire Stent Electrode as a Minimally Invasive Endovascular Neural Interface
title_fullStr Laser Welding of Micro-Wire Stent Electrode as a Minimally Invasive Endovascular Neural Interface
title_full_unstemmed Laser Welding of Micro-Wire Stent Electrode as a Minimally Invasive Endovascular Neural Interface
title_short Laser Welding of Micro-Wire Stent Electrode as a Minimally Invasive Endovascular Neural Interface
title_sort laser welding of micro wire stent electrode as a minimally invasive endovascular neural interface
topic endovascular stent electrode
laser welding
electrochemical impedance spectroscopy (EIS)
minimally invasive brain–computer interface
url https://www.mdpi.com/2072-666X/16/1/21
work_keys_str_mv AT bowen laserweldingofmicrowirestentelectrodeasaminimallyinvasiveendovascularneuralinterface
AT liangshen laserweldingofmicrowirestentelectrodeasaminimallyinvasiveendovascularneuralinterface
AT xiaoyangkang laserweldingofmicrowirestentelectrodeasaminimallyinvasiveendovascularneuralinterface