Application of rapid evaporative ionization mass spectrometry in preclinical and clinical analyses of steatotic liver tissues and cells

Application of rapid evaporative ionization mass spectrometry in preclinical and clinical analyses of steatotic liver tissues and cells

Abstract Rapid evaporative ionization mass spectrometry (REIMS) shows promise as a preparation-free tissue analysis tool with the prospect for real-time diagnostics. Given that hepatic steatosis is characterized by shifts in lipid species and abundance, we selected it as basis for method development...

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Main Authors: Julian Connor Eckel, Lena Seidemann, Mohamed Albadry, Gerda Schicht, Marija Skvoznikova, Sandra Nickel, René Hänsel, Daniel Seehofer, Grit Gesine Ruth Hiller, Hans-Michael Tautenhahn, Uta Dahmen, Georg Damm
Format: Article
Language:English
Published: Nature Portfolio 2025-03-01
Series:Scientific Reports
Subjects:
Rapid evaporative ionization mass spectrometry
MASLD
Lipidomics
Steatosis
Lipids
Online Access:https://doi.org/10.1038/s41598-025-93305-w
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https://doi.org/10.1038/s41598-025-93305-w

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