Mathematical modelling and simulation analysis of a modified Butterworth van Dyke circuit model for non‐invasive diabetes detection

In recent times, there is an intense need for a reliable non‐invasive diabetes prediction system. Some of the researches in this field suggest that acetone gas in breath has a good correlation to blood glucose levels. Hence, acetone is emerging as a promising bio‐marker in diabetes prediction. In th...

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Main Authors: Srinivasan Lekha, Suchetha Manikandan
Format: Article
Language:English
Published: Wiley 2017-11-01
Series:IET Circuits, Devices and Systems
Subjects:
Online Access:https://doi.org/10.1049/iet-cds.2017.0002
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author Srinivasan Lekha
Suchetha Manikandan
author_facet Srinivasan Lekha
Suchetha Manikandan
author_sort Srinivasan Lekha
collection DOAJ
description In recent times, there is an intense need for a reliable non‐invasive diabetes prediction system. Some of the researches in this field suggest that acetone gas in breath has a good correlation to blood glucose levels. Hence, acetone is emerging as a promising bio‐marker in diabetes prediction. In this study, acetone levels are measured using quartz crystal microbalance sensor that has wide‐scale application as a bio‐sensor. It is a piezoelectric sensor which is used to detect and quantify mass variations. The resonant frequency of the sensor changes when there is a deposition of mass on the surface of the crystal. The shift in resonant frequency is directly proportional to the change in the mass concentration. To estimate the performance of this sensor, it is required to understand the sensor's electrical characteristics such as its conductance gain and admittance. This study studies these characteristics and evaluates the behaviour of the sensor in the presence of various acetone concentrations in breath sample for healthy, type 1 and type 2 diabetic subjects.
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spelling doaj-art-a8077454f55f4e85a56f5b91c3909ae22025-02-03T01:32:08ZengWileyIET Circuits, Devices and Systems1751-858X1751-85982017-11-0111668268710.1049/iet-cds.2017.0002Mathematical modelling and simulation analysis of a modified Butterworth van Dyke circuit model for non‐invasive diabetes detectionSrinivasan Lekha0Suchetha Manikandan1School of Electronics EngineeringVellore Institute of TechnologyChennai CampusChennaiTamil NaduIndiaSchool of Electronics EngineeringVellore Institute of TechnologyChennai CampusChennaiTamil NaduIndiaIn recent times, there is an intense need for a reliable non‐invasive diabetes prediction system. Some of the researches in this field suggest that acetone gas in breath has a good correlation to blood glucose levels. Hence, acetone is emerging as a promising bio‐marker in diabetes prediction. In this study, acetone levels are measured using quartz crystal microbalance sensor that has wide‐scale application as a bio‐sensor. It is a piezoelectric sensor which is used to detect and quantify mass variations. The resonant frequency of the sensor changes when there is a deposition of mass on the surface of the crystal. The shift in resonant frequency is directly proportional to the change in the mass concentration. To estimate the performance of this sensor, it is required to understand the sensor's electrical characteristics such as its conductance gain and admittance. This study studies these characteristics and evaluates the behaviour of the sensor in the presence of various acetone concentrations in breath sample for healthy, type 1 and type 2 diabetic subjects.https://doi.org/10.1049/iet-cds.2017.0002mathematical modellingsimulation analysismodified Butterworth van Dyke circuit modelnoninvasive diabetes detectionreliable noninvasive diabetes prediction systemacetone gas
spellingShingle Srinivasan Lekha
Suchetha Manikandan
Mathematical modelling and simulation analysis of a modified Butterworth van Dyke circuit model for non‐invasive diabetes detection
IET Circuits, Devices and Systems
mathematical modelling
simulation analysis
modified Butterworth van Dyke circuit model
noninvasive diabetes detection
reliable noninvasive diabetes prediction system
acetone gas
title Mathematical modelling and simulation analysis of a modified Butterworth van Dyke circuit model for non‐invasive diabetes detection
title_full Mathematical modelling and simulation analysis of a modified Butterworth van Dyke circuit model for non‐invasive diabetes detection
title_fullStr Mathematical modelling and simulation analysis of a modified Butterworth van Dyke circuit model for non‐invasive diabetes detection
title_full_unstemmed Mathematical modelling and simulation analysis of a modified Butterworth van Dyke circuit model for non‐invasive diabetes detection
title_short Mathematical modelling and simulation analysis of a modified Butterworth van Dyke circuit model for non‐invasive diabetes detection
title_sort mathematical modelling and simulation analysis of a modified butterworth van dyke circuit model for non invasive diabetes detection
topic mathematical modelling
simulation analysis
modified Butterworth van Dyke circuit model
noninvasive diabetes detection
reliable noninvasive diabetes prediction system
acetone gas
url https://doi.org/10.1049/iet-cds.2017.0002
work_keys_str_mv AT srinivasanlekha mathematicalmodellingandsimulationanalysisofamodifiedbutterworthvandykecircuitmodelfornoninvasivediabetesdetection
AT suchethamanikandan mathematicalmodellingandsimulationanalysisofamodifiedbutterworthvandykecircuitmodelfornoninvasivediabetesdetection