Lymphoepithelioma-Like Carcinoma of the Breast: A Case Report Unveiling Several Clinical and Histopathological Challenges
Lymphoepithelioma-like carcinoma (LELC) of the breast is an extremely rare tumor type. Histologically, it mimics undifferentiated nasopharyngeal carcinoma by demonstrating nests of neoplastic epithelial cells in a background of lymphoplasmacytic infiltrates. This paper reports a 62-year-old female p...
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| Format: | Article |
| Language: | English |
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Wiley
2018-01-01
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| Series: | Case Reports in Surgery |
| Online Access: | http://dx.doi.org/10.1155/2018/8240534 |
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| author | Tarek Aridi Mohamad Fawwaz Ahmad Kassab Marwan Bahmad Faisal Houcheimi Mohamad Mshiek Fouad Boulos Ali Kanj Ghassan Ramadan Hisham F. Bahmad Najla Fakhruddin |
| author_facet | Tarek Aridi Mohamad Fawwaz Ahmad Kassab Marwan Bahmad Faisal Houcheimi Mohamad Mshiek Fouad Boulos Ali Kanj Ghassan Ramadan Hisham F. Bahmad Najla Fakhruddin |
| author_sort | Tarek Aridi |
| collection | DOAJ |
| description | Lymphoepithelioma-like carcinoma (LELC) of the breast is an extremely rare tumor type. Histologically, it mimics undifferentiated nasopharyngeal carcinoma by demonstrating nests of neoplastic epithelial cells in a background of lymphoplasmacytic infiltrates. This paper reports a 62-year-old female patient with a 3 × 1.5 cm BI-RADS type IV breast mass diagnosed on excisional biopsy as LELC. The tumor is negative for estrogen and progesterone receptors and did not overexpress HER2/neu. Routine tests for clearance before surgery were performed, and patient was managed by a modified radical mastectomy with axillary lymph node dissection showing no residual tumor. Surgical CAse REports (SCARE) guidelines were followed for reporting our case. The rarity of LELC of the breast warrants the establishment and implementation of well-defined guidelines and criteria for diagnosis and management. |
| format | Article |
| id | doaj-art-a7ef9c5f669145ccba90f87586ff808b |
| institution | Kabale University |
| issn | 2090-6900 2090-6919 |
| language | English |
| publishDate | 2018-01-01 |
| publisher | Wiley |
| record_format | Article |
| series | Case Reports in Surgery |
| spelling | doaj-art-a7ef9c5f669145ccba90f87586ff808b2025-02-03T01:12:48ZengWileyCase Reports in Surgery2090-69002090-69192018-01-01201810.1155/2018/82405348240534Lymphoepithelioma-Like Carcinoma of the Breast: A Case Report Unveiling Several Clinical and Histopathological ChallengesTarek Aridi0Mohamad Fawwaz1Ahmad Kassab2Marwan Bahmad3Faisal Houcheimi4Mohamad Mshiek5Fouad Boulos6Ali Kanj7Ghassan Ramadan8Hisham F. Bahmad9Najla Fakhruddin10Faculty of Medicine, American University of Beirut, Beirut, LebanonFaculty of Medicine, Beirut Arab University, Beirut, LebanonFaculty of Medicine, Beirut Arab University, Beirut, LebanonFaculty of Medicine, Beirut Arab University, Beirut, LebanonFaculty of Medicine, Beirut Arab University, Beirut, LebanonFaculty of Medicine, Beirut Arab University, Beirut, LebanonDepartment of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, LebanonDepartment of Radiology, Hammoud Hospital University Medical Center, Saida, LebanonDepartment of General Surgery, Hammoud Hospital University Medical Center, Saida, LebanonDepartment of Anatomy, Cell Biology and Physiological Sciences, Faculty of Medicine, American University of Beirut, Beirut, LebanonDepartment of Pathology and Laboratory Medicine, American University of Beirut Medical Center, Beirut, LebanonLymphoepithelioma-like carcinoma (LELC) of the breast is an extremely rare tumor type. Histologically, it mimics undifferentiated nasopharyngeal carcinoma by demonstrating nests of neoplastic epithelial cells in a background of lymphoplasmacytic infiltrates. This paper reports a 62-year-old female patient with a 3 × 1.5 cm BI-RADS type IV breast mass diagnosed on excisional biopsy as LELC. The tumor is negative for estrogen and progesterone receptors and did not overexpress HER2/neu. Routine tests for clearance before surgery were performed, and patient was managed by a modified radical mastectomy with axillary lymph node dissection showing no residual tumor. Surgical CAse REports (SCARE) guidelines were followed for reporting our case. The rarity of LELC of the breast warrants the establishment and implementation of well-defined guidelines and criteria for diagnosis and management.http://dx.doi.org/10.1155/2018/8240534 |
| spellingShingle | Tarek Aridi Mohamad Fawwaz Ahmad Kassab Marwan Bahmad Faisal Houcheimi Mohamad Mshiek Fouad Boulos Ali Kanj Ghassan Ramadan Hisham F. Bahmad Najla Fakhruddin Lymphoepithelioma-Like Carcinoma of the Breast: A Case Report Unveiling Several Clinical and Histopathological Challenges Case Reports in Surgery |
| title | Lymphoepithelioma-Like Carcinoma of the Breast: A Case Report Unveiling Several Clinical and Histopathological Challenges |
| title_full | Lymphoepithelioma-Like Carcinoma of the Breast: A Case Report Unveiling Several Clinical and Histopathological Challenges |
| title_fullStr | Lymphoepithelioma-Like Carcinoma of the Breast: A Case Report Unveiling Several Clinical and Histopathological Challenges |
| title_full_unstemmed | Lymphoepithelioma-Like Carcinoma of the Breast: A Case Report Unveiling Several Clinical and Histopathological Challenges |
| title_short | Lymphoepithelioma-Like Carcinoma of the Breast: A Case Report Unveiling Several Clinical and Histopathological Challenges |
| title_sort | lymphoepithelioma like carcinoma of the breast a case report unveiling several clinical and histopathological challenges |
| url | http://dx.doi.org/10.1155/2018/8240534 |
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