Reference Interval for Cystatin C in a Sample of Adult Cuban Population

<strong>Foundation:</strong> studying cystatin C has risen interest as it is defined its utility as an early marker and sensitive to chronic renal disease. Determining the range of reference for chemical analysis in clinical laboratories constitutes an essential requirement to implement...

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Main Author: Dailen Darias Rivera
Format: Article
Language:Spanish
Published: Universidad de las Ciencias Médicas de Cienfuegos 2020-06-01
Series:Revista Finlay
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Online Access:https://revfinlay.sld.cu/index.php/finlay/article/view/698
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author Dailen Darias Rivera
author_facet Dailen Darias Rivera
author_sort Dailen Darias Rivera
collection DOAJ
description <strong>Foundation:</strong> studying cystatin C has risen interest as it is defined its utility as an early marker and sensitive to chronic renal disease. Determining the range of reference for chemical analysis in clinical laboratories constitutes an essential requirement to implement an adequate quality control program. <strong><br />Objective:</strong> to establish the interval of reference of Cystatin C in a sample of adult Cuban population, in the laboratory of the Clinical Surgical Hospital Hermanos Ameijeiras. <strong><br />Method:</strong> cross-descriptive study in 249 blood donors (women and men in the same proportion), aged between 18 and 50. By the inmunoturbidimetric method the values of seric cystatin C were obtained and were compared by sex and age group. The interval of reference was calculated and compared with the one proposed by the manufacturer. <strong><br />Results:</strong> the interval of reference obtained showed association with sex, but not with the age group. Statistically significant differences were found between the interval of seric reference of cystatin C in both sexes and the one proposed by the manufacturer. <strong><br />Conclusion:</strong> the need of counting with values of reference according to each place was evidenced, according to the International Federation of Clinical Chemistry and the standards of clinical laboratory.
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spelling doaj-art-a7e9bfe7d33c4e9891bca646627c85042025-01-30T21:22:00ZspaUniversidad de las Ciencias Médicas de CienfuegosRevista Finlay2221-24342020-06-01102107117445Reference Interval for Cystatin C in a Sample of Adult Cuban PopulationDailen Darias Rivera0Complejo Científico Ortopédico Internacional Frank País. La Habana.<strong>Foundation:</strong> studying cystatin C has risen interest as it is defined its utility as an early marker and sensitive to chronic renal disease. Determining the range of reference for chemical analysis in clinical laboratories constitutes an essential requirement to implement an adequate quality control program. <strong><br />Objective:</strong> to establish the interval of reference of Cystatin C in a sample of adult Cuban population, in the laboratory of the Clinical Surgical Hospital Hermanos Ameijeiras. <strong><br />Method:</strong> cross-descriptive study in 249 blood donors (women and men in the same proportion), aged between 18 and 50. By the inmunoturbidimetric method the values of seric cystatin C were obtained and were compared by sex and age group. The interval of reference was calculated and compared with the one proposed by the manufacturer. <strong><br />Results:</strong> the interval of reference obtained showed association with sex, but not with the age group. Statistically significant differences were found between the interval of seric reference of cystatin C in both sexes and the one proposed by the manufacturer. <strong><br />Conclusion:</strong> the need of counting with values of reference according to each place was evidenced, according to the International Federation of Clinical Chemistry and the standards of clinical laboratory.https://revfinlay.sld.cu/index.php/finlay/article/view/698cistatina cvalores de referenciaadulto
spellingShingle Dailen Darias Rivera
Reference Interval for Cystatin C in a Sample of Adult Cuban Population
Revista Finlay
cistatina c
valores de referencia
adulto
title Reference Interval for Cystatin C in a Sample of Adult Cuban Population
title_full Reference Interval for Cystatin C in a Sample of Adult Cuban Population
title_fullStr Reference Interval for Cystatin C in a Sample of Adult Cuban Population
title_full_unstemmed Reference Interval for Cystatin C in a Sample of Adult Cuban Population
title_short Reference Interval for Cystatin C in a Sample of Adult Cuban Population
title_sort reference interval for cystatin c in a sample of adult cuban population
topic cistatina c
valores de referencia
adulto
url https://revfinlay.sld.cu/index.php/finlay/article/view/698
work_keys_str_mv AT dailendariasrivera referenceintervalforcystatincinasampleofadultcubanpopulation