Determination of Glyphosate, Glufosinate, and Their Major Metabolites in Tea Infusions by Dual-Channel Capillary Electrophoresis following Solid-Phase Extraction

In this study, two analytical procedures were developed and validated using dual-channel capillary electrophoresis-coupled contactless conductivity detection (CE-C4D) followed by solid-phase extraction (SPE) for simultaneous determination of glyphosate (GLYP), glufosinate (GLUF), and their two major...

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Main Authors: Manh Huy Nguyen, Thanh Dam Nguyen, Minh Tuan Vu, Hong Anh Duong, Hung Viet Pham
Format: Article
Language:English
Published: Wiley 2022-01-01
Series:Journal of Analytical Methods in Chemistry
Online Access:http://dx.doi.org/10.1155/2022/5687025
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author Manh Huy Nguyen
Thanh Dam Nguyen
Minh Tuan Vu
Hong Anh Duong
Hung Viet Pham
author_facet Manh Huy Nguyen
Thanh Dam Nguyen
Minh Tuan Vu
Hong Anh Duong
Hung Viet Pham
author_sort Manh Huy Nguyen
collection DOAJ
description In this study, two analytical procedures were developed and validated using dual-channel capillary electrophoresis-coupled contactless conductivity detection (CE-C4D) followed by solid-phase extraction (SPE) for simultaneous determination of glyphosate (GLYP), glufosinate (GLUF), and their two major metabolites, aminomethylphosphonic acid (AMPA) and 3-(methylphosphinico) propionic acid (MPPA), respectively, in a popular beverage such as tea infusions. GLYP, GLUF, and AMPA were analyzed in the first channel using background electrolyte (BGE) of 1 mM histidine (His) adjusted to pH 2.75 by acetic acid (Ace). In contrast, MPPA was quantified in the second channel with a BGE of 30 mM His adjusted to pH 6.7 by 3-(N-morpholino) propanesulfonic acid (MOPS) and 10 µM of cetyltrimethylammonium bromide (CTAB). In addition, the samples of tea infusions were treated using SPE with 10 mL of 0.5 mM HCl in methanol as eluent. At the optimized conditions, the method detection limit (MDL) of GLYP, GLUF, AMPA, and MPPA is 0.80, 1.56, 0.56, and 0.54 μg/l, respectively. The methods were then applied to analyze four target compounds in 16 samples of tea infusions. GLYP was found in two infusion samples of oolong tea with concentrations ranging from 5.34 to 10.74 µg/L, and GLUF was recognized in three samples of green tea infusion in the range of 45.1–53.9 µg/L.
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spelling doaj-art-a7e3f93fcafd43b0a30f327ab85c0de62025-08-20T03:38:48ZengWileyJournal of Analytical Methods in Chemistry2090-88732022-01-01202210.1155/2022/5687025Determination of Glyphosate, Glufosinate, and Their Major Metabolites in Tea Infusions by Dual-Channel Capillary Electrophoresis following Solid-Phase ExtractionManh Huy Nguyen0Thanh Dam Nguyen1Minh Tuan Vu2Hong Anh Duong3Hung Viet Pham4Key Laboratory of Analytical Technology for Environmental Quality and Food Safety Control (KLATEFOS)Key Laboratory of Analytical Technology for Environmental Quality and Food Safety Control (KLATEFOS)Key Laboratory of Analytical Technology for Environmental Quality and Food Safety Control (KLATEFOS)Key Laboratory of Analytical Technology for Environmental Quality and Food Safety Control (KLATEFOS)Key Laboratory of Analytical Technology for Environmental Quality and Food Safety Control (KLATEFOS)In this study, two analytical procedures were developed and validated using dual-channel capillary electrophoresis-coupled contactless conductivity detection (CE-C4D) followed by solid-phase extraction (SPE) for simultaneous determination of glyphosate (GLYP), glufosinate (GLUF), and their two major metabolites, aminomethylphosphonic acid (AMPA) and 3-(methylphosphinico) propionic acid (MPPA), respectively, in a popular beverage such as tea infusions. GLYP, GLUF, and AMPA were analyzed in the first channel using background electrolyte (BGE) of 1 mM histidine (His) adjusted to pH 2.75 by acetic acid (Ace). In contrast, MPPA was quantified in the second channel with a BGE of 30 mM His adjusted to pH 6.7 by 3-(N-morpholino) propanesulfonic acid (MOPS) and 10 µM of cetyltrimethylammonium bromide (CTAB). In addition, the samples of tea infusions were treated using SPE with 10 mL of 0.5 mM HCl in methanol as eluent. At the optimized conditions, the method detection limit (MDL) of GLYP, GLUF, AMPA, and MPPA is 0.80, 1.56, 0.56, and 0.54 μg/l, respectively. The methods were then applied to analyze four target compounds in 16 samples of tea infusions. GLYP was found in two infusion samples of oolong tea with concentrations ranging from 5.34 to 10.74 µg/L, and GLUF was recognized in three samples of green tea infusion in the range of 45.1–53.9 µg/L.http://dx.doi.org/10.1155/2022/5687025
spellingShingle Manh Huy Nguyen
Thanh Dam Nguyen
Minh Tuan Vu
Hong Anh Duong
Hung Viet Pham
Determination of Glyphosate, Glufosinate, and Their Major Metabolites in Tea Infusions by Dual-Channel Capillary Electrophoresis following Solid-Phase Extraction
Journal of Analytical Methods in Chemistry
title Determination of Glyphosate, Glufosinate, and Their Major Metabolites in Tea Infusions by Dual-Channel Capillary Electrophoresis following Solid-Phase Extraction
title_full Determination of Glyphosate, Glufosinate, and Their Major Metabolites in Tea Infusions by Dual-Channel Capillary Electrophoresis following Solid-Phase Extraction
title_fullStr Determination of Glyphosate, Glufosinate, and Their Major Metabolites in Tea Infusions by Dual-Channel Capillary Electrophoresis following Solid-Phase Extraction
title_full_unstemmed Determination of Glyphosate, Glufosinate, and Their Major Metabolites in Tea Infusions by Dual-Channel Capillary Electrophoresis following Solid-Phase Extraction
title_short Determination of Glyphosate, Glufosinate, and Their Major Metabolites in Tea Infusions by Dual-Channel Capillary Electrophoresis following Solid-Phase Extraction
title_sort determination of glyphosate glufosinate and their major metabolites in tea infusions by dual channel capillary electrophoresis following solid phase extraction
url http://dx.doi.org/10.1155/2022/5687025
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