Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls

BACKGROUND: Leptin, an adipocyte-produced cytokine, interacts with various hormones, including those of the hypothalamic-pituitary-adrenal axis. Fibromyalgia is a syndrome characterized by widespread pain accompanied by tenderness. The pathogenesis involves a disturbance in pain processing and trans...

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Main Authors: Jacob N Ablin, Natalia Aronov, Ilan Shimon, Hannah Kanety, Clara Pariente, Valerie Aloush, Ori Elkayam, David Levartovsky
Format: Article
Language:English
Published: Wiley 2012-01-01
Series:Pain Research and Management
Online Access:http://dx.doi.org/10.1155/2012/350654
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author Jacob N Ablin
Natalia Aronov
Ilan Shimon
Hannah Kanety
Clara Pariente
Valerie Aloush
Ori Elkayam
David Levartovsky
author_facet Jacob N Ablin
Natalia Aronov
Ilan Shimon
Hannah Kanety
Clara Pariente
Valerie Aloush
Ori Elkayam
David Levartovsky
author_sort Jacob N Ablin
collection DOAJ
description BACKGROUND: Leptin, an adipocyte-produced cytokine, interacts with various hormones, including those of the hypothalamic-pituitary-adrenal axis. Fibromyalgia is a syndrome characterized by widespread pain accompanied by tenderness. The pathogenesis involves a disturbance in pain processing and transmission by the central nervous system, leading to a general increase in pain perception.
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series Pain Research and Management
spelling doaj-art-a7d07c7acf3b4e5584a6329e2aaca3d82025-02-03T01:10:00ZengWileyPain Research and Management1203-67652012-01-01172899210.1155/2012/350654Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy ControlsJacob N Ablin0Natalia Aronov1Ilan Shimon2Hannah Kanety3Clara Pariente4Valerie Aloush5Ori Elkayam6David Levartovsky7Department of Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelInternal Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelInstitute of Endocrinology Metabolism and Diabetes, Rabin Medical Center, Petach – Tikvah, IsraelThe Institute of Endocrinology, Sheba Medical Center, Tel-Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv, IsraelThe Institute of Endocrinology, Sheba Medical Center, Tel-Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv, IsraelDepartment of Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelDepartment of Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelDepartment of Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelBACKGROUND: Leptin, an adipocyte-produced cytokine, interacts with various hormones, including those of the hypothalamic-pituitary-adrenal axis. Fibromyalgia is a syndrome characterized by widespread pain accompanied by tenderness. The pathogenesis involves a disturbance in pain processing and transmission by the central nervous system, leading to a general increase in pain perception.http://dx.doi.org/10.1155/2012/350654
spellingShingle Jacob N Ablin
Natalia Aronov
Ilan Shimon
Hannah Kanety
Clara Pariente
Valerie Aloush
Ori Elkayam
David Levartovsky
Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls
Pain Research and Management
title Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls
title_full Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls
title_fullStr Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls
title_full_unstemmed Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls
title_short Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls
title_sort evaluation of leptin levels among fibromyalgia patients before and after three months of treatment in comparison with healthy controls
url http://dx.doi.org/10.1155/2012/350654
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