Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls
BACKGROUND: Leptin, an adipocyte-produced cytokine, interacts with various hormones, including those of the hypothalamic-pituitary-adrenal axis. Fibromyalgia is a syndrome characterized by widespread pain accompanied by tenderness. The pathogenesis involves a disturbance in pain processing and trans...
Saved in:
Main Authors: | , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2012-01-01
|
Series: | Pain Research and Management |
Online Access: | http://dx.doi.org/10.1155/2012/350654 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
_version_ | 1832564906543546368 |
---|---|
author | Jacob N Ablin Natalia Aronov Ilan Shimon Hannah Kanety Clara Pariente Valerie Aloush Ori Elkayam David Levartovsky |
author_facet | Jacob N Ablin Natalia Aronov Ilan Shimon Hannah Kanety Clara Pariente Valerie Aloush Ori Elkayam David Levartovsky |
author_sort | Jacob N Ablin |
collection | DOAJ |
description | BACKGROUND: Leptin, an adipocyte-produced cytokine, interacts with various hormones, including those of the hypothalamic-pituitary-adrenal axis. Fibromyalgia is a syndrome characterized by widespread pain accompanied by tenderness. The pathogenesis involves a disturbance in pain processing and transmission by the central nervous system, leading to a general increase in pain perception. |
format | Article |
id | doaj-art-a7d07c7acf3b4e5584a6329e2aaca3d8 |
institution | Kabale University |
issn | 1203-6765 |
language | English |
publishDate | 2012-01-01 |
publisher | Wiley |
record_format | Article |
series | Pain Research and Management |
spelling | doaj-art-a7d07c7acf3b4e5584a6329e2aaca3d82025-02-03T01:10:00ZengWileyPain Research and Management1203-67652012-01-01172899210.1155/2012/350654Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy ControlsJacob N Ablin0Natalia Aronov1Ilan Shimon2Hannah Kanety3Clara Pariente4Valerie Aloush5Ori Elkayam6David Levartovsky7Department of Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelInternal Medicine, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelInstitute of Endocrinology Metabolism and Diabetes, Rabin Medical Center, Petach – Tikvah, IsraelThe Institute of Endocrinology, Sheba Medical Center, Tel-Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv, IsraelThe Institute of Endocrinology, Sheba Medical Center, Tel-Hashomer, Sackler School of Medicine, Tel Aviv University, Tel Aviv, IsraelDepartment of Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelDepartment of Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelDepartment of Rheumatology, Tel Aviv Sourasky Medical Center, Tel Aviv, IsraelBACKGROUND: Leptin, an adipocyte-produced cytokine, interacts with various hormones, including those of the hypothalamic-pituitary-adrenal axis. Fibromyalgia is a syndrome characterized by widespread pain accompanied by tenderness. The pathogenesis involves a disturbance in pain processing and transmission by the central nervous system, leading to a general increase in pain perception.http://dx.doi.org/10.1155/2012/350654 |
spellingShingle | Jacob N Ablin Natalia Aronov Ilan Shimon Hannah Kanety Clara Pariente Valerie Aloush Ori Elkayam David Levartovsky Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls Pain Research and Management |
title | Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls |
title_full | Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls |
title_fullStr | Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls |
title_full_unstemmed | Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls |
title_short | Evaluation of Leptin Levels among Fibromyalgia Patients before and after Three Months of Treatment, in Comparison with Healthy Controls |
title_sort | evaluation of leptin levels among fibromyalgia patients before and after three months of treatment in comparison with healthy controls |
url | http://dx.doi.org/10.1155/2012/350654 |
work_keys_str_mv | AT jacobnablin evaluationofleptinlevelsamongfibromyalgiapatientsbeforeandafterthreemonthsoftreatmentincomparisonwithhealthycontrols AT nataliaaronov evaluationofleptinlevelsamongfibromyalgiapatientsbeforeandafterthreemonthsoftreatmentincomparisonwithhealthycontrols AT ilanshimon evaluationofleptinlevelsamongfibromyalgiapatientsbeforeandafterthreemonthsoftreatmentincomparisonwithhealthycontrols AT hannahkanety evaluationofleptinlevelsamongfibromyalgiapatientsbeforeandafterthreemonthsoftreatmentincomparisonwithhealthycontrols AT clarapariente evaluationofleptinlevelsamongfibromyalgiapatientsbeforeandafterthreemonthsoftreatmentincomparisonwithhealthycontrols AT valeriealoush evaluationofleptinlevelsamongfibromyalgiapatientsbeforeandafterthreemonthsoftreatmentincomparisonwithhealthycontrols AT orielkayam evaluationofleptinlevelsamongfibromyalgiapatientsbeforeandafterthreemonthsoftreatmentincomparisonwithhealthycontrols AT davidlevartovsky evaluationofleptinlevelsamongfibromyalgiapatientsbeforeandafterthreemonthsoftreatmentincomparisonwithhealthycontrols |