PP2Acα regulates sleep amount and sleep homeostasis in mice

PP2Acα regulates sleep amount and sleep homeostasis in mice

Abstract Genetic studies in mice have identified multiple sleep-regulating protein kinases, but the sleep functions of protein phosphatases remain largely unclear. Here, we performed adeno-associated virus-mediated somatic genetics analysis of PP2A catalytic subunits–PP2Acα and PP2Acβ–in sleep regul...

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Main Authors: Shuang Zhou, Bihan Shi, Lin Chen, Xin Yin, Minghao Liu, Chongyang Wu, Haiyan Wang, Xia Wang, Bin Li, Fengchao Wang, Qi Li, Qinghua Liu
Format: Article
Language:English
Published: Nature Portfolio 2025-07-01
Series:Communications Biology
Online Access:https://doi.org/10.1038/s42003-025-08437-6
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