The potential role of BCL2A1⁺ tissue-resident macrophages in the prognosis of Wilms tumor

The potential role of BCL2A1⁺ tissue-resident macrophages in the prognosis of Wilms tumor

Abstract Tumor-associated macrophages (TAMs) have a significant impact on the prognosis and treatment outcomes of Wilms tumor (WT) patients. To explore the key mechanisms underlying WT progression and immune therapy, this study used CIBERSORT to analyze the immune cell infiltration of 120 WT patient...

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Bibliographic Details
Main Authors: Wei Wang, Xianwu Yang, Zhihui Zhu, Zhishen Tang, Yingquan Zhuo, Jun Du, Yuxian Zhu, Xi Luo, Jingjing Xiao, Huajian Gu
Format: Article
Language:English
Published: BMC 2025-07-01
Series:European Journal of Medical Research
Subjects:
BCL2A1
Wilms tumor
Tissue-resident macrophages
Prognostic significance
Tumor microenvironment
Online Access:https://doi.org/10.1186/s40001-025-02935-3
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