Metastatic extension of Ewing’s sarcoma to the right heart chambers: a rare case report

Abstract Background Ewing’s sarcoma (ES) is a common malignant bone tumor in adolescents and young adults. Its pelvic location is associated with a worse prognosis. Our case represents one of the rare instances in the literature involving an adult patient in whom the disease progressed fatally due t...

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Main Authors: Yassine Ettagmouti, Salah-Eddine Hayar, Ilyas Atlas, Ghita Bennani, Meryem Haboub, Rachida Habbal
Format: Article
Language:English
Published: SpringerOpen 2025-02-01
Series:The Egyptian Heart Journal
Online Access:https://doi.org/10.1186/s43044-025-00619-1
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author Yassine Ettagmouti
Salah-Eddine Hayar
Ilyas Atlas
Ghita Bennani
Meryem Haboub
Rachida Habbal
author_facet Yassine Ettagmouti
Salah-Eddine Hayar
Ilyas Atlas
Ghita Bennani
Meryem Haboub
Rachida Habbal
author_sort Yassine Ettagmouti
collection DOAJ
description Abstract Background Ewing’s sarcoma (ES) is a common malignant bone tumor in adolescents and young adults. Its pelvic location is associated with a worse prognosis. Our case represents one of the rare instances in the literature involving an adult patient in whom the disease progressed fatally due to cardiac extension. Case presentation We report the case of a 31-year-old female patient who initially presented with swelling in her right lower extremity, which was found to be caused by deep venous thrombosis (DVT) extending from the iliac vein to the inferior vena cava. A thoracic-abdominal CT scan, performed as part of the etiological workup, revealed a tumor in the right hip bone with a malignant appearance, exhibiting both endo and exopelvic extension, and extending to the inferior vena cava (IVC) and right heart chambers. An echo-guided biopsy of the tumor mass confirmed Ewing's sarcoma. The patient's condition rapidly deteriorated, leading to death due to the inoperability of the extensive tumor. Conclusions Ewing’s sarcoma can affect adults, presenting with late-onset or rapidly metastatic forms. In its extensive form, ES requires multimodal imaging to assess operability and is associated with a poor prognosis. This case report represents one of the rare instances in the literature of Ewing’s sarcoma metastasizing to the heart.
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issn 2090-911X
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series The Egyptian Heart Journal
spelling doaj-art-a79e06ccde3345c691f4069d0c20ed4c2025-08-20T03:04:12ZengSpringerOpenThe Egyptian Heart Journal2090-911X2025-02-017711610.1186/s43044-025-00619-1Metastatic extension of Ewing’s sarcoma to the right heart chambers: a rare case reportYassine Ettagmouti0Salah-Eddine Hayar1Ilyas Atlas2Ghita Bennani3Meryem Haboub4Rachida Habbal5Cardiology Division, Ibn Rochd University HospitalCardiology Division, Ibn Rochd University HospitalCardiology Division, Ibn Rochd University HospitalRadiology Division, 20 AOUT 1953 HospitalCardiology Division, Ibn Rochd University HospitalCardiology Division, Ibn Rochd University HospitalAbstract Background Ewing’s sarcoma (ES) is a common malignant bone tumor in adolescents and young adults. Its pelvic location is associated with a worse prognosis. Our case represents one of the rare instances in the literature involving an adult patient in whom the disease progressed fatally due to cardiac extension. Case presentation We report the case of a 31-year-old female patient who initially presented with swelling in her right lower extremity, which was found to be caused by deep venous thrombosis (DVT) extending from the iliac vein to the inferior vena cava. A thoracic-abdominal CT scan, performed as part of the etiological workup, revealed a tumor in the right hip bone with a malignant appearance, exhibiting both endo and exopelvic extension, and extending to the inferior vena cava (IVC) and right heart chambers. An echo-guided biopsy of the tumor mass confirmed Ewing's sarcoma. The patient's condition rapidly deteriorated, leading to death due to the inoperability of the extensive tumor. Conclusions Ewing’s sarcoma can affect adults, presenting with late-onset or rapidly metastatic forms. In its extensive form, ES requires multimodal imaging to assess operability and is associated with a poor prognosis. This case report represents one of the rare instances in the literature of Ewing’s sarcoma metastasizing to the heart.https://doi.org/10.1186/s43044-025-00619-1
spellingShingle Yassine Ettagmouti
Salah-Eddine Hayar
Ilyas Atlas
Ghita Bennani
Meryem Haboub
Rachida Habbal
Metastatic extension of Ewing’s sarcoma to the right heart chambers: a rare case report
The Egyptian Heart Journal
title Metastatic extension of Ewing’s sarcoma to the right heart chambers: a rare case report
title_full Metastatic extension of Ewing’s sarcoma to the right heart chambers: a rare case report
title_fullStr Metastatic extension of Ewing’s sarcoma to the right heart chambers: a rare case report
title_full_unstemmed Metastatic extension of Ewing’s sarcoma to the right heart chambers: a rare case report
title_short Metastatic extension of Ewing’s sarcoma to the right heart chambers: a rare case report
title_sort metastatic extension of ewing s sarcoma to the right heart chambers a rare case report
url https://doi.org/10.1186/s43044-025-00619-1
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AT ilyasatlas metastaticextensionofewingssarcomatotherightheartchambersararecasereport
AT ghitabennani metastaticextensionofewingssarcomatotherightheartchambersararecasereport
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