POSITIVE IMPACT OF INFUSION WITH LEVOSIMENDAN ON THE ELDER PATIENTS (60-75 YEARS OLD) WITH LOWER EJECTION FRACTION OF THE LEFT VENTRICLE (< 50%) IN THE PERI-OPERATIVE PERIOD IN NON-CARDIAC SURGERY
Pre-surgery infusion with levosimendan with the rate of 0.05–0.1 mkg*kg-1 min-1 to the elder patients (60–75 years old) with lower ejection fraction of the left ventricle (less than 50%) results in its increase by 16.7% (p < 0.01), cardiac index – by 10.3% (p >< 0.01) and reduct...
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| Format: | Article |
| Language: | Russian |
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New Terra Publishing House
2018-01-01
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| Series: | Вестник анестезиологии и реаниматологии |
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| Online Access: | https://www.vair-journal.com/jour/article/view/85 |
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| author | Yu. V. Ubasev Yu. V. Skripkin T. S. Zabelina V. A. Sungurov V. V. Lomivorotov D. N. Marchenko V. V. Likhvantsev |
| author_facet | Yu. V. Ubasev Yu. V. Skripkin T. S. Zabelina V. A. Sungurov V. V. Lomivorotov D. N. Marchenko V. V. Likhvantsev |
| author_sort | Yu. V. Ubasev |
| collection | DOAJ |
| description | Pre-surgery infusion with levosimendan with the rate of 0.05–0.1 mkg*kg-1 min-1 to the elder patients (60–75 years old) with lower ejection fraction of the left ventricle (less than 50%) results in its increase by 16.7% (p < 0.01), cardiac index – by 10.3% (p >< 0.01) and reduction of NT-proBNP level in blood by 24.1% (p >< 0.1) in 24 hours after the medication infusion start. The changes persist for at least 24 hours after the surgery. Key words: levosimendan, cardiac failure, peri-operative period, pre-surgery preparation, cardiac surgery, reduction of NT-proBNP level.>< 0.01), cardiac index – by 10.3% (p< 0.01) and reduction of NT-proBNP level in blood by 24.1% (p < 0.1) in 24 hours after the medication infusion start. The changes persist for at least 24 hours after the surgery. Key words: levosimendan, cardiac failure, peri-operative period, pre-surgery preparation, cardiac surgery, reduction of NT-proBNP level.>< 0.1) in 24 hours after the medication infusion start. The changes persist for at least 24 hours after the surgery. |
| format | Article |
| id | doaj-art-a79dac2c8a9a48649a21edd2774c921c |
| institution | DOAJ |
| issn | 2078-5658 2541-8653 |
| language | Russian |
| publishDate | 2018-01-01 |
| publisher | New Terra Publishing House |
| record_format | Article |
| series | Вестник анестезиологии и реаниматологии |
| spelling | doaj-art-a79dac2c8a9a48649a21edd2774c921c2025-08-20T02:59:46ZrusNew Terra Publishing HouseВестник анестезиологии и реаниматологии2078-56582541-86532018-01-01132293610.21292/2078-5658-2016-13-2-29-3685POSITIVE IMPACT OF INFUSION WITH LEVOSIMENDAN ON THE ELDER PATIENTS (60-75 YEARS OLD) WITH LOWER EJECTION FRACTION OF THE LEFT VENTRICLE (< 50%) IN THE PERI-OPERATIVE PERIOD IN NON-CARDIAC SURGERYYu. V. Ubasev0Yu. V. Skripkin1T. S. Zabelina2V. A. Sungurov3V. V. Lomivorotov4D. N. Marchenko5V. V. Likhvantsev6Military Medical Organisation, Golytsino, Moscow RegionM. F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow; V. A. Negovsky Institute of General Critical Care, MoscowM. F. Vladimirsky Moscow Regional Research Clinical Institute, MoscowMilitary Medical Organisation, Golytsino, Moscow RegionE. N. Meshalkin Research Institute of Blood Circulation Pathology, NovosibirskMunicipal Clinical Hospital no. 81, Moscow Health Department, MoscowM. F. Vladimirsky Moscow Regional Research Clinical Institute, Moscow; V. A. Negovsky Institute of General Critical Care, MoscowPre-surgery infusion with levosimendan with the rate of 0.05–0.1 mkg*kg-1 min-1 to the elder patients (60–75 years old) with lower ejection fraction of the left ventricle (less than 50%) results in its increase by 16.7% (p < 0.01), cardiac index – by 10.3% (p >< 0.01) and reduction of NT-proBNP level in blood by 24.1% (p >< 0.1) in 24 hours after the medication infusion start. The changes persist for at least 24 hours after the surgery. Key words: levosimendan, cardiac failure, peri-operative period, pre-surgery preparation, cardiac surgery, reduction of NT-proBNP level.>< 0.01), cardiac index – by 10.3% (p< 0.01) and reduction of NT-proBNP level in blood by 24.1% (p < 0.1) in 24 hours after the medication infusion start. The changes persist for at least 24 hours after the surgery. Key words: levosimendan, cardiac failure, peri-operative period, pre-surgery preparation, cardiac surgery, reduction of NT-proBNP level.>< 0.1) in 24 hours after the medication infusion start. The changes persist for at least 24 hours after the surgery.https://www.vair-journal.com/jour/article/view/85levosimendancardiac failureperi-operative periodpre-surgery preparationcardiac surgeryreduction of nt-probnp level |
| spellingShingle | Yu. V. Ubasev Yu. V. Skripkin T. S. Zabelina V. A. Sungurov V. V. Lomivorotov D. N. Marchenko V. V. Likhvantsev POSITIVE IMPACT OF INFUSION WITH LEVOSIMENDAN ON THE ELDER PATIENTS (60-75 YEARS OLD) WITH LOWER EJECTION FRACTION OF THE LEFT VENTRICLE (< 50%) IN THE PERI-OPERATIVE PERIOD IN NON-CARDIAC SURGERY Вестник анестезиологии и реаниматологии levosimendan cardiac failure peri-operative period pre-surgery preparation cardiac surgery reduction of nt-probnp level |
| title | POSITIVE IMPACT OF INFUSION WITH LEVOSIMENDAN ON THE ELDER PATIENTS (60-75 YEARS OLD) WITH LOWER EJECTION FRACTION OF THE LEFT VENTRICLE (< 50%) IN THE PERI-OPERATIVE PERIOD IN NON-CARDIAC SURGERY |
| title_full | POSITIVE IMPACT OF INFUSION WITH LEVOSIMENDAN ON THE ELDER PATIENTS (60-75 YEARS OLD) WITH LOWER EJECTION FRACTION OF THE LEFT VENTRICLE (< 50%) IN THE PERI-OPERATIVE PERIOD IN NON-CARDIAC SURGERY |
| title_fullStr | POSITIVE IMPACT OF INFUSION WITH LEVOSIMENDAN ON THE ELDER PATIENTS (60-75 YEARS OLD) WITH LOWER EJECTION FRACTION OF THE LEFT VENTRICLE (< 50%) IN THE PERI-OPERATIVE PERIOD IN NON-CARDIAC SURGERY |
| title_full_unstemmed | POSITIVE IMPACT OF INFUSION WITH LEVOSIMENDAN ON THE ELDER PATIENTS (60-75 YEARS OLD) WITH LOWER EJECTION FRACTION OF THE LEFT VENTRICLE (< 50%) IN THE PERI-OPERATIVE PERIOD IN NON-CARDIAC SURGERY |
| title_short | POSITIVE IMPACT OF INFUSION WITH LEVOSIMENDAN ON THE ELDER PATIENTS (60-75 YEARS OLD) WITH LOWER EJECTION FRACTION OF THE LEFT VENTRICLE (< 50%) IN THE PERI-OPERATIVE PERIOD IN NON-CARDIAC SURGERY |
| title_sort | positive impact of infusion with levosimendan on the elder patients 60 75 years old with lower ejection fraction of the left ventricle 50 in the peri operative period in non cardiac surgery |
| topic | levosimendan cardiac failure peri-operative period pre-surgery preparation cardiac surgery reduction of nt-probnp level |
| url | https://www.vair-journal.com/jour/article/view/85 |
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